OBJECTIVE: To review the literature on nicotine dependence, nicotine pharmacology,
health consequences associated with the use of nicotine, and nicotine replacement …

BACKGROUND: Nicotine replacement therapy (NRT) doubles successful quitting, but more
than half of NRT users do not comply with optimal treatment regimens. METHODS: From the …

Aim s To identify promising intervention components intended to help smokers to attain and
maintain abstinence in their quit smoking attempts. Design A fully crossed, six‐factor …

Smoking-cessation drugs are inadequate at addressing the behavioural component of
tobacco dependence. Nicotine-free inhalators are plastic devices that may provide a coping …

Aims To identify promising intervention components that help smokers attain and maintain
abstinence during a quit attempt. Design A 2× 2× 2× 2× 2 randomized factorial experiment …

Background: In spite of an established safety and efficacy record, nicotine replacement
therapy (NRT) is frequently used incorrectly, suboptimally, or not at all. Objective: This article …

Nicotine replacement therapy (NRT) has added to the menu of options available to assist
cigarette smokers in quit attempts, but cost remains a barrier to access. A quasi …

Background. The reasons for relapse to smoking are not fully understood but several factors
are of importance. Addiction to nicotine seems to play a prominent role but there are several …

In 1996, the FDA approved over-the-counter (OTC) availability of nicotine gum and two
brands of nicotine skin patches. Little is known about how this reclassification has influenced …

Objective: To determine whether over-the-counter (OTC) nicotine replacement therapy
(NRT) is pharmacologically efficacious, whether it produces abstinence rates similar to those …