Under disease conditions including obesity (insulin resistance) and diabetes, dysregulation
of adipokines such as tumor necrosis factor (TNF)-α, leptin, resistin, and adiponectin …

Adiponectin secreted from adipose tissue binds to two distinct adiponectin receptors
(AdipoR1 and AdipoR2) identified and exerts its anti-diabetic effects in insulin-sensitive …

Several adipocyte-secreted factors have been demonstrated to potentially link obesity,
insulin resistance, and cardiovascular disease. Among those, adiponectin is an insulin …

Background: Adiponectin is an adipocyte-derived cytokine closely associated with obesity,
altered body adipose tissue distribution, insulin resistance, and cardiovascular diseases …

Adiponectin and adiponectin receptors (AdipoRs) have been found to play significant roles
in the etiology of obesity-related chronic disease. Their discovery has been a long and …

Obesity is strongly associated with metabolic and cardiovascular disorders. Adiponectin is
an adipose-derived plasma protein that is downregulated in subjects with obesity-related …

Adiponectin is produced predominantly by adipocytes and plays an important role in
metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti …

Nearly 1 in 4 adults in the United States is obese. The connection between obesity and
insulin resistance, type 2 diabetes, and cardiovascular disease is a well researched one …

Studies performed during the last decade indicate that adipose tissue is not only a site of
triglyceride storage but also an active endocrine organ which secretes many biologically …

Adiponectin is an adipokine predominantly produced by fat cells, circulates and exerts
insulin-sensitizing, cardioprotective and anti-inflammatory effects. Dysregulation of …