Synthesis of 2′, 4′-propylene-bridged (carba-ENA) thymidine and its analogues: the engineering of electrostatic and steric effects at the bottom of the minor groove …

Y Liu, J Xu, M Karimiahmadabadi, C Zhou… - The Journal of …, 2010 - ACS Publications
2′, 4′-Propylene-bridged thymidine (carba-ENA-T) and five 8′-Me/NH2/OH modified
carba-ENA-T analogues have been prepared through intramolecular radical addition to C …

Synthesis of 3 '-3 '-Linked Oligonucleotides Branched by a Pentaerythritol Linker and the Thermal Stabilities of the Triplexes with Single-Stranded DNA or RNA

Y Ueno, A Shibata, A Matsuda, Y Kitade - Bioconjugate chemistry, 2003 - ACS Publications
Synthesis of 3 '-3 '-linked oligonucleotides branched by a pentaerythritol linker is described.
The branched oligonucleotides were synthesized on a DNA/RNA synthesizer using a …

[HTML][HTML] Synthesis and properties of oligonucleotides modified with an N-methylguanidine-bridged nucleic acid (GuNA [Me]) bearing adenine, guanine, or 5 …

N Horie, T Yamaguchi, S Kumagai… - Beilstein Journal of …, 2021 - beilstein-journals.org
Chemical modifications have been extensively used for therapeutic oligonucleotides
because they strongly enhance the stability against nucleases, binding affinity to the targets …

Nucleosides and nucleotides. 162. Facile synthesis of 5′-5′-linked oligodeoxyribonucleotides with the potential for triple-helix formation

Y Ueno, A Ogawa, A Nakagawa, A Matsuda - Bioorganic & Medicinal …, 1996 - Elsevier
The facile synthesis of 5′-5′-linked oligodeoxyribonucleotides (ODNs) with the potential
for triple-helix formation is described. ODNs containing 5-trifluoroethoxycarbonyl-2 …

Synthesis and hybridization properties of β-and α-oligodeoxynucleotides containing β-and α-1-(3-C-allyl-2-deoxy-D-erythro-pentofuranosyl) thymine and α-1-[3-C-(3 …

PN Jørgensen, US Sørensen, HM Pfundheller… - Journal of the …, 1997 - pubs.rsc.org
Convergent synthesis of β-and α-1-(3-C-allyl-2-deoxy-D-erythro-pentofuranosyl) thymine
and their incorporation into β-and α-oligodeoxynucleotides (ODNs) is described. The …

Mild and facile deprotection for the synthesis of oligodeoxynucleotide incorporating a 6-O-ethyl-deoxyguanosine

K Seio, T Negishi, K Negishi… - Letters in Organic …, 2005 - okayama.elsevierpure.com
The phenoxyacetyl (Pac) group proved to be useful for the synthesis of
oligodeoxyribonucleotides incorporating a 6-O-ethylguanine. Since the Pac group could be …

Synthesis of an oligonucleotide analogue of ethenoadenosine

N Koissi, H Lönnberg - Nucleosides, Nucleotides and Nucleic Acids, 2003 - Taylor & Francis
Synthesis of an Oligonucleotide Analogue of Ethenoadenosine Page 1 Synthesis of an
Oligonucleotide Analogue of Ethenoadenosine Niangoran Koissi* and Harri Lönnberg …

The synthesis of oligoribonucleotides containing N6‐alkyladenosines and 2‐methylthio‐N6‐alkyladenosines via post‐synthetic modification of precursor oligomers

E Kierzek, R Kierzek - Nucleic acids research, 2003 - academic.oup.com
Abstract The N 6‐alkyladenosines and 2‐methylthio‐N 6‐alkyladenosines are the most
common modified adenosine nucleosides and transfer ribonucleic acids (tRNA) are …

Oligonucleotides containing a nucleotide analog with an ethynylfluorobenzene as nucleobase surrogate

N Griesang, C Richert - Tetrahedron letters, 2002 - Elsevier
The 5′-protected 3′-phosphoramidite of 1-(2′-deoxy-β-d-ribofuranosyl)-2-ethynyl-4-
fluorobenzene was prepared and employed in the synthesis of oligonucleotides. The duplex …

Synthetic use of epoxy-sugar nucleosides

H Tanaka, Y Kubota, S Takeda… - … Nucleotides, and Nucleic …, 2007 - Taylor & Francis
Full article: Synthetic Use Of Epoxy-Sugar Nucleosides Skip to Main Content Taylor and Francis
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