Novel non-invasive particles in exhaled air method to explore the lining fluid of small airways—a European population-based cohort study
L Hussain-Alkhateeb, B Bake… - BMJ open …, 2021 - bmjopenrespres.bmj.com
Introduction Respiratory tract lining fluid of small airways mainly consists of surfactant that
can be investigated by collection of the particles of exhaled aerosol (PExA) method. This …
can be investigated by collection of the particles of exhaled aerosol (PExA) method. This …
Intra-individual variation of particles in exhaled air and of the contents of Surfactant protein A and albumin
S Kokelj, JL Kim, M Andersson, G Runström Eden… - PLoS …, 2020 - journals.plos.org
Introduction Particles in exhaled air (PEx) provide samples of respiratory tract lining fluid
from small airways containing, for example, Surfactant protein A (SP-A) and albumin …
from small airways containing, for example, Surfactant protein A (SP-A) and albumin …
Particles in exhaled air (PExA): non-invasive phenotyping of small airways disease in adult asthma
M Soares, E Mirgorodskaya, H Koca… - Journal of breath …, 2018 - iopscience.iop.org
Rationale: Asthma is often characterised by inflammation, damage and dysfunction of the
small airways, but no standardised biomarkers are available. Objectives: Using a novel …
small airways, but no standardised biomarkers are available. Objectives: Using a novel …
Current smoking alters phospholipid-and surfactant protein A levels in small airway lining fluid: An explorative study on exhaled breath
E Viklund, B Bake, L Hussain-Alkhateeb… - PLoS …, 2021 - journals.plos.org
Small airways are difficult to access. Exhaled droplets, also referred to as particles, provide a
sample of small airway lining fluid and may reflect inflammatory responses. We aimed to …
sample of small airway lining fluid and may reflect inflammatory responses. We aimed to …
Surfactant Protein A in particles in exhaled air (PExA), bronchial lavage and bronchial wash-a methodological comparison
AF Behndig, E Mirgorodskaya, A Blomberg… - Respiratory research, 2019 - Springer
Introduction At present, there are few methods available for monitoring respiratory diseases
affecting distal airways. Bronchoscopy is the golden standard for sampling the lower …
affecting distal airways. Bronchoscopy is the golden standard for sampling the lower …
[HTML][HTML] Surfactant protein A in particles in exhaled air and plasma
H Koca, A Farbrot, AC Olin, ÖI Emilsson - Respiratory Physiology & …, 2022 - Elsevier
Respiratory tract lining fluid (RTLF) is an important component of the lung epithelial barrier.
Pathological changes in RTLF may cause increased permeability of the epithelial barrier …
Pathological changes in RTLF may cause increased permeability of the epithelial barrier …
Exhaled breath particles as a novel tool to study lipid composition of epithelial lining fluid from the distal lung
P Larsson, O Holz, G Koster, A Postle, AC Olin… - BMC Pulmonary …, 2023 - Springer
Background Surfactant phospholipid (PL) composition plays an important role in lung
diseases. We compared the PL composition of non-invasively collected exhaled breath …
diseases. We compared the PL composition of non-invasively collected exhaled breath …
Surfactant protein A in exhaled endogenous particles is decreased in chronic obstructive pulmonary disease (COPD) patients: a pilot study
M Lärstad, AC Almstrand, P Larsson, B Bake… - PLoS …, 2015 - journals.plos.org
Background Exhaled, endogenous particles are formed from the epithelial lining fluid in
small airways, where surfactant protein A (SP-A) plays an important role in pulmonary host …
small airways, where surfactant protein A (SP-A) plays an important role in pulmonary host …
Comparison of exhaled endogenous particles from smokers and non-smokers using multivariate analysis
A Bredberg, M Josefson, AC Almstrand, J Lausmaa… - Respiration, 2013 - karger.com
Background: Smoking, along with many respiratory diseases, has been shown to induce
airway inflammation and alter the composition of the respiratory tract lining fluid (RTLF). We …
airway inflammation and alter the composition of the respiratory tract lining fluid (RTLF). We …
Exhaled particles and small airways
B Bake, P Larsson, G Ljungkvist, E Ljungström… - Respiratory …, 2019 - Springer
Background Originally, studies on exhaled droplets explored properties of airborne
transmission of infectious diseases. More recently, the interest focuses on properties of …
transmission of infectious diseases. More recently, the interest focuses on properties of …
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