Efficacy and tolerability of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus
KB Harris, DJ McCarty - Therapeutic Advances in …, 2015 - journals.sagepub.com
Glucagon-like peptide-1 (GLP-1) has been evaluated for use in the treatment of type 2
diabetes mellitus (T2DM) due to its role in glucose regulation. Four GLP-1 receptor agonists …
diabetes mellitus (T2DM) due to its role in glucose regulation. Four GLP-1 receptor agonists …
[PDF][PDF] Mechanisms of action and therapeutic application of glucagon-like peptide-1
DJ Drucker - Cell metabolism, 2018 - cell.com
Glucagon-like peptide-1 (GLP-1) released from gut enteroendocrine cells controls meal-
related glycemic excursions through augmentation of insulin and inhibition of glucagon …
related glycemic excursions through augmentation of insulin and inhibition of glucagon …
A review of GLP‐1 receptor agonists: evolution and advancement, through the lens of randomised controlled trials
VR Aroda - Diabetes, Obesity and Metabolism, 2018 - Wiley Online Library
Aims To review the evolution and advancement of GLP‐1 receptor agonist (GLP‐1RA)
therapy, through the lens of randomised controlled trials, from differentiating characteristics …
therapy, through the lens of randomised controlled trials, from differentiating characteristics …
[HTML][HTML] Glucagon-like peptide-1 receptor agonists in type 2 diabetes: their use and differential features
KA Lyseng-Williamson - Clinical Drug Investigation, 2019 - Springer
Glucagon-like peptide-1 receptor analogues/agonists (GLP-1RAs) are well established as
effective adjuncts to lifestyle modification in the treatment of type 2 diabetes (T2D) as …
effective adjuncts to lifestyle modification in the treatment of type 2 diabetes (T2D) as …
[HTML][HTML] GLP-1 based therapeutics: simultaneously combating T2DM and obesity
KM Heppner, D Perez-Tilve - Frontiers in neuroscience, 2015 - frontiersin.org
Glucagon-like peptide-1 (GLP-1) enhances meal-related insulin secretion, which lowers
blood glucose excursions. In addition to its incretin action, GLP-1 acts on the GLP-1 receptor …
blood glucose excursions. In addition to its incretin action, GLP-1 acts on the GLP-1 receptor …
Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities
Abstract Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone, secreted in
response to ingestion of nutrients, and has important effects on several of the …
response to ingestion of nutrients, and has important effects on several of the …
GLP-1 receptor agonists: an updated review of head-to-head clinical studies
JM Trujillo, W Nuffer, BA Smith - Therapeutic advances in …, 2021 - journals.sagepub.com
Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are attractive options for the
treatment of type 2 diabetes (T2D) because they effectively lower A1C and weight while …
treatment of type 2 diabetes (T2D) because they effectively lower A1C and weight while …
Targeting the glucagon receptor family for diabetes and obesity therapy
YM Cho, CE Merchant, TJ Kieffer - Pharmacology & therapeutics, 2012 - Elsevier
Diabetes is a debilitating disease characterized by chronic hyperglycemia and is often
associated with obesity. With diabetes and obesity incidence on the rise, it is imperative to …
associated with obesity. With diabetes and obesity incidence on the rise, it is imperative to …
[HTML][HTML] Cardiovascular effects of glucagon-like peptide 1 (GLP-1) receptor agonists
FK Saraiva, AC Sposito - Cardiovascular Diabetology, 2014 - Springer
Patients with type 2 diabetes have a several-fold increased risk of developing
cardiovascular disease when compared with nondiabetic controls. Myocardial infarction and …
cardiovascular disease when compared with nondiabetic controls. Myocardial infarction and …
[HTML][HTML] Incretin-based therapy: a powerful and promising weapon in the treatment of type 2 diabetes mellitus
C Koliaki, J Doupis - Diabetes Therapy, 2011 - Springer
Type 2 diabetes mellitus (T2DM) is a progressive multisystemic disease that increases
significantly cardiovascular morbidity and mortality. It is associated with obesity, insulin …
significantly cardiovascular morbidity and mortality. It is associated with obesity, insulin …