Methods have been developed to allow quantitative connectivity of the whole fixed mouse
brain by means of magnetic resonance imaging (MRI). We have translated what we have …

Diffusion tensor histology holds great promise for quantitative characterization of structural
connectivity in mouse models of neurological and psychiatric conditions. There has been …

Systematic mapping of long-distance pathways in the human brain (the “macro-
connectome”) represents a grand challenge for the coming century. Diffusion imaging and …

Interest in structural brain connectivity has grown with the understanding that abnormal
neural connections may play a role in neurologic and psychiatric diseases. Small animal …

Decades of detailed anatomical tracer studies in non-human animals point to a rich and
complex organization of long-range white matter connections in the brain. State-of-the art in …

Understanding the connectivity architecture of entire vertebrate brains is a fundamental but
difficult task. Here we present an integrated neuro-histological pipeline as well as a grid …

Non-invasive measuring methods such as EEG/MEG, fMRI and DTI are increasingly utilised
to extract quantitative information on functional and anatomical connectivity in the human …

A complete structural definition of the human nervous system must include delineation of its
wiring diagram (eg, Swanson LW. Brain architecture: understanding the basic plan, 2012) …

Tractography combined with regions of interest (ROIs) has been used to non-invasively
study the structural connectivity of the cortex as well as to assess the reliability of these …

Brain cells communicate with one another via local and long-range synaptic connections.
Structural connectivity is the foundation for neural function. Brain-wide connectivity can be …