Novel copper (II) complexes as new promising antitumour agents. A crystal structure of [Cu (1, 10-phenanthroline-5, 6-dione) 2 (OH2)(OClO3)](ClO4)

T Pivetta, F Trudu, E Valletta, F Isaia… - Journal of Inorganic …, 2014 - Elsevier
The cytotoxic properties of copper (II) complexes with 1, 10-phenanthroline (phen) can be
modified by substitution in the phen backbone. For this purpose, Cu (II) complexes with …

A mixed‐ligand copper (II) complex that inhibits growth and induces apoptosis by DNA targeting in human epithelial cervical cancer cells

ZY Ma, Z Qiao, DB Wang, X Hou, X Qiao… - Applied …, 2017 - Wiley Online Library
A new mixed‐ligand copper (II) complex,[Cu (L)(phen)]⋅ MeOH (L= 4‐chloro‐2‐[(2‐
hydroxyphenyl) iminomethyl] phenol), was synthesized. It belongs to the orthorhombic …

Synthesis, structural characterization and cytotoxic activity against tumor cells of heteroleptic copper (I) complexes with aromatic diimines and phosphines

N Alvarez, C Noble, MH Torre, E Kremer, J Ellena… - Inorganica Chimica …, 2017 - Elsevier
Copper coordination complexes are increasingly recognized as potential drugs for
therapeutic use in various diseases, especially in cancer. In an attempt to find new leaders …

Correlation between DNA interactions and cytotoxic activity of four new ternary compounds of copper (II) with N-donor heterocyclic ligands

PP Silva, W Guerra, GC Dos Santos… - Journal of Inorganic …, 2014 - Elsevier
Four new ternary complexes of copper (II) were synthesized and characterized:[Cu
(hyd)(bpy)(acn)(ClO 4)](ClO 4)](1),[Cu (hyd)(phen)(acn)(ClO 4)](ClO 4)](2),[Cu …

Synthesis, Characterization And Antitumor Activity Of Copper(II) Complexes, [CuL2] [HL1-3=N,N‐Diethyl‐N′‐(R‐Benzoyl)Thiourea (R=H, o‐Cl and p‐NO2)]

W Hernández, E Spodine, L Beyer… - Bioinorganic …, 2005 - Wiley Online Library
The copper (II) complexes (CuL2) were prepared by reaction of Cu (CH 3 COO) 2 with the
corresponding derivatives of acylthioureas in a Cu: HL molar ratio of 1: 2. Acylthiourea …

Synthesis, structural characterization, cytotoxic properties and DNA binding of a dinuclear copper (II) complex

BJML Ferreira, P Brandão, M Meireles, F Martel… - Journal of Inorganic …, 2016 - Elsevier
In this study a novel dinuclear copper (II) complex with adenine and phenanthroline has
been synthesized and its structure determined by single crystal X-ray diffraction. In the …

Cytotoxic copper (II) mixed ligand complexes: Crystal structure and DNA cleavage activity

VM Manikandamathavan, RP Parameswari… - European journal of …, 2011 - Elsevier
Two new mixed ligand complexes of copper (II) containing an imidazolyl terpyridine
ligand,[Cu (Itpy)(bpy)](ClO4) 2·(H2O), 1, and [Cu (Itpy)(phen)(ClO4)](ClO4)·(H2O), 2 have …

Synthesis, structural characterization and cytotoxic activity of ternary copper (II)–dipeptide–phenanthroline complexes. A step towards the development of new copper …

S Iglesias, N Alvarez, MH Torre, E Kremer… - Journal of Inorganic …, 2014 - Elsevier
In the search for new compounds with antitumor activity, coordination complexes with
different metals are being studied by our group. This work presents the synthesis and …

Synthesis, electronic structure, DNA and protein binding, DNA cleavage, and anticancer activity of fluorophore-labeled copper (II) complexes

SS Bhat, AA Kumbhar, H Heptullah, AA Khan… - Inorganic …, 2011 - ACS Publications
Two mononuclear fluorophore-labeled copper (II) complexes [Cu (nip)(acac)]+(2) and [Cu
(nip) 2] 2+(3), where fluorophore is 2-(naphthalen-1-yl)-1 H-imidazo [4, 5-f][1, 10] …

Copper (II): phenanthroline complexes with l-asparagine and l-methionine: Synthesis, crystal structure and in-vitro cytotoxic effects on prostate, breast and melanoma …

JAO Rodrigues, JG de Oliveira Neto, AOS de Barros… - Polyhedron, 2020 - Elsevier
Here we report the cytotoxic effects of the two ternary copper (II) complexes [Cu (Phen)(l-
methionine) H 2 O] Cl· 1.5 H 2 O (Cu (PHEN)(MET)) and [Cu (Phen)(l-asparagine) H 2 OCl] …