Comparison of experimental rat models of early brain injury after subarachnoid hemorrhage

JY Lee, O Sagher, R Keep, Y Hua, G Xi - Neurosurgery, 2009 - journals.lww.com
OBJECTIVE: To investigate acute pathophysiological changes after subarachnoid
hemorrhage (SAH) in rats and compare endovascular perforation and double blood …

Experimental subarachnoid hemorrhage: subarachnoid blood volume, mortality rate, neuronal death, cerebral blood flow, and perfusion pressure in three different rat …

GF Prunell, T Mathiesen, NH Diemer… - Neurosurgery, 2003 - journals.lww.com
OBJECTIVE: To investigate which of three subarachnoid hemorrhage (SAH) models is the
most suitable for studies of pathological and pathophysiological processes after SAH …

Characteristics of cerebrovascular injury in the hyperacute phase after induced severe subarachnoid hemorrhage

Y Hasegawa, H Suzuki, K Uekawa, T Kawano… - Translational stroke …, 2015 - Springer
Although there have been several investigations regarding acute brain injury after
subarachnoid hemorrhage (SAH), the pathological conditions of severe SAH are unclear. In …

Cortical blood flow and cerebral perfusion pressure in a new noncraniotomy model of subarachnoid hemorrhage in the rat

JB Bederson, IM Germano, L Guarino - Stroke, 1995 - Am Heart Assoc
Background and Purpose Acute cerebral ischemia after subarachnoid hemorrhage (SAH) is
a major cause of morbidity whose precise etiology is unclear. The purpose of this study was …

Brain edema formation and neurological impairment after subarachnoid hemorrhage in rats

SC Thal, S Sporer, M Klopotowski, SE Thal… - Journal of …, 2009 - thejns.org
Object Global cerebral edema is an independent risk factor for early death and poor
outcome after subarachnoid hemorrhage (SAH). In the present study, the time course of …

Experimental subarachnoid hemorrhage: cerebral blood flow and brain metabolism during the acute phase in three different models in the rat

GF Prunell, T Mathiesen, NA Svendgaard - Neurosurgery, 2004 - journals.lww.com
OBJECTIVE: To study the cerebral metabolism and its relationship to cerebral blood flow
(CBF) acutely after subarachnoid hemorrhage (SAH). METHODS: SAH was induced in rats …

Rat endovascular perforation model

FA Sehba - Translational stroke research, 2014 - Springer
Experimental animal models of aneurysmal subarachnoid hemorrhage (SAH) have provided
a wealth of information on the mechanisms of brain injury. The rat endovascular perforation …

MRI characterization in the acute phase of experimental subarachnoid hemorrhage

D Guo, DA Wilkinson, BG Thompson… - Translational stroke …, 2017 - Springer
A number of mechanisms have been proposed for the early brain injury after subarachnoid
hemorrhage (SAH). In this study, we investigated the radiographic characteristics and …

Acute vasoconstriction after subarachnoid hemorrhage

JB Bederson, AL Levy, WH Ding, R Kahn… - …, 1998 - journals.lww.com
OBJECTIVE: Decreased cerebral blood flow (CBF) and cerebral ischemia occurring
immediately after subarachnoid hemorrhage (SAH) may be caused by acute microvascular …

Time-course of cerebral perfusion and tissue oxygenation in the first 6 h after experimental subarachnoid hemorrhage in rats

T Westermaier, A Jauss, J Eriskat… - Journal of Cerebral …, 2009 - journals.sagepub.com
Present knowledge about hemodynamic and metabolic changes after subarachnoid
hemorrhage (SAH) originates from neuromonitoring usually starting with aneurysm surgery …