Early events in endothelial flow sensing
Responses of vascular and lymphatic endothelial cells (ECs) to fluid shear stress (FSS) from
blood or lymphatic fluid flow govern the development, physiology, and diseases of these …
blood or lymphatic fluid flow govern the development, physiology, and diseases of these …
Effects of morphological patterning on endothelial cell migration
The migration of vascular endothelial cells (ECs) plays an important role in vascular
remodeling. Here we studied the effects of cell morphology on the migration of bovine aortic …
remodeling. Here we studied the effects of cell morphology on the migration of bovine aortic …
Biochemistry and biomechanics of cell motility
S Li, JL Guan, S Chien - Annu. Rev. Biomed. Eng., 2005 - annualreviews.org
▪ Abstract Cell motility is an essential cellular process for a variety of biological events. The
process of cell migration requires the integration and coordination of complex biochemical …
process of cell migration requires the integration and coordination of complex biochemical …
Signalling mechanisms in the regulation of vascular cell migration
H Abedi, I Zachary - Cardiovascular research, 1995 - academic.oup.com
The migration of arterial vascular smooth muscle cells (VSMC) is thought to play a central
role in atherogenesis and restenosis. The migration of several other cell types, including …
role in atherogenesis and restenosis. The migration of several other cell types, including …
Microtopography and flow modulate the direction of endothelial cell migration
P Uttayarat, M Chen, M Li, FD Allen… - American Journal …, 2008 - journals.physiology.org
The migration of vascular endothelial cells under flow can be modulated by the addition of
chemical or mechanical stimuli. The aim of this study was to investigate how topographic …
chemical or mechanical stimuli. The aim of this study was to investigate how topographic …
[HTML][HTML] Mechanosignalling pathways that regulate endothelial barrier function
A McQueen, CM Warboys - Current Opinion in Cell Biology, 2023 - Elsevier
Blood vessels are lined by a single layer of endothelial cells that provide a barrier between
circulating plasma and the underlying tissue. Permeability of endothelial cells is tightly …
circulating plasma and the underlying tissue. Permeability of endothelial cells is tightly …
Fluid flow mechanotransduction in vascular smooth muscle cells and fibroblasts
ZD Shi, JM Tarbell - Annals of biomedical engineering, 2011 - Springer
Understanding how vascular wall endothelial cells (ECs), smooth muscle cells (SMCs), and
fibroblasts (FBs) sense and transduce the stimuli of hemodynamic forces (shear stress …
fibroblasts (FBs) sense and transduce the stimuli of hemodynamic forces (shear stress …
Vascular mechanobiology endothelial cell responses to fluid shear stress
J Ando, K Yamamoto - Circulation Journal, 2009 - jstage.jst.go.jp
Endothelial cells (ECs) lining blood vessel walls respond to shear stress, a fluid mechanical
force generated by flowing blood, and the EC responses play an important role in the …
force generated by flowing blood, and the EC responses play an important role in the …
Differential responsiveness of vascular endothelial cells to different types of fluid mechanical shear stress
AI Barakat, DK Lieu - Cell biochemistry and biophysics, 2003 - Springer
Early atherosclerotic lesions localize preferentially, in arterial regions exposed to low flow,
oscillatory flow, or both; however, the cellular basis of this observation remains to be …
oscillatory flow, or both; however, the cellular basis of this observation remains to be …
[HTML][HTML] Endothelial cell alignment as a result of anisotropic strain and flow induced shear stress combinations
Endothelial cells (ECs) are continuously exposed in vivo to cyclic strain and shear stress
from pulsatile blood flow. When these stimuli are applied in vitro, ECs adopt an appearance …
from pulsatile blood flow. When these stimuli are applied in vitro, ECs adopt an appearance …