Early events in endothelial flow sensing

K Tanaka, D Joshi, S Timalsina, MA Schwartz - Cytoskeleton, 2021 - Wiley Online Library
Responses of vascular and lymphatic endothelial cells (ECs) to fluid shear stress (FSS) from
blood or lymphatic fluid flow govern the development, physiology, and diseases of these …

Effects of morphological patterning on endothelial cell migration

S Li, S Bhatia, YL Hu, YT Shiu, YS Li, S Usami… - …, 2001 - content.iospress.com
The migration of vascular endothelial cells (ECs) plays an important role in vascular
remodeling. Here we studied the effects of cell morphology on the migration of bovine aortic …

Biochemistry and biomechanics of cell motility

S Li, JL Guan, S Chien - Annu. Rev. Biomed. Eng., 2005 - annualreviews.org
▪ Abstract Cell motility is an essential cellular process for a variety of biological events. The
process of cell migration requires the integration and coordination of complex biochemical …

Signalling mechanisms in the regulation of vascular cell migration

H Abedi, I Zachary - Cardiovascular research, 1995 - academic.oup.com
The migration of arterial vascular smooth muscle cells (VSMC) is thought to play a central
role in atherogenesis and restenosis. The migration of several other cell types, including …

Microtopography and flow modulate the direction of endothelial cell migration

P Uttayarat, M Chen, M Li, FD Allen… - American Journal …, 2008 - journals.physiology.org
The migration of vascular endothelial cells under flow can be modulated by the addition of
chemical or mechanical stimuli. The aim of this study was to investigate how topographic …

[HTML][HTML] Mechanosignalling pathways that regulate endothelial barrier function

A McQueen, CM Warboys - Current Opinion in Cell Biology, 2023 - Elsevier
Blood vessels are lined by a single layer of endothelial cells that provide a barrier between
circulating plasma and the underlying tissue. Permeability of endothelial cells is tightly …

Fluid flow mechanotransduction in vascular smooth muscle cells and fibroblasts

ZD Shi, JM Tarbell - Annals of biomedical engineering, 2011 - Springer
Understanding how vascular wall endothelial cells (ECs), smooth muscle cells (SMCs), and
fibroblasts (FBs) sense and transduce the stimuli of hemodynamic forces (shear stress …

Vascular mechanobiology endothelial cell responses to fluid shear stress

J Ando, K Yamamoto - Circulation Journal, 2009 - jstage.jst.go.jp
Endothelial cells (ECs) lining blood vessel walls respond to shear stress, a fluid mechanical
force generated by flowing blood, and the EC responses play an important role in the …

Differential responsiveness of vascular endothelial cells to different types of fluid mechanical shear stress

AI Barakat, DK Lieu - Cell biochemistry and biophysics, 2003 - Springer
Early atherosclerotic lesions localize preferentially, in arterial regions exposed to low flow,
oscillatory flow, or both; however, the cellular basis of this observation remains to be …

[HTML][HTML] Endothelial cell alignment as a result of anisotropic strain and flow induced shear stress combinations

R Sinha, S Le Gac, N Verdonschot, A van den Berg… - Scientific reports, 2016 - nature.com
Endothelial cells (ECs) are continuously exposed in vivo to cyclic strain and shear stress
from pulsatile blood flow. When these stimuli are applied in vitro, ECs adopt an appearance …