Reactive oxygen species (ROS) have been implicated in the pathogenesis of numerous
disease processes. Epithelial cells lining the respiratory airways are uniquely vulnerable …

Oxygen free radicals and their metabolites, collectively described as reactive oxygen
species (ROS), have been implicated in the pathogenesis of many diseases. The pulmonary …

In vivoexposure to ozone (O3) has been shown to cause airway epithelial damage and lipid
peroxidation. The oxidation of polyunsaturated fatty acids has been shown to produce …

Reactive oxygen species may be generated by several inflammatory cells which participate
in airway inflammation and their production may be increased in asthma. Oxygen …

The health effect of atmospheric pollution is causing increasing public concern. Several
controlled human-exposure studies have clearly. shown that oxidant pollutants, including …

This review describes production and effects of reactive oxygen species (ROS) on airway
function. ROS are important in many physiological processes but can also have detrimental …

Ozone (O 3) is the major oxidant of photochemical smog. Its biological effect is attributed to
its stability to cause oxidation or peroxidation of biomolecules directly and/or via free radical …

As eukaryotic life evolved, so too did the need for a source of energy that meets the
requirements of complex organisms. Oxygen provides this vast potential energy source, but …

T here is overwhelming evidence that oxidants, free radicals that scavenge electrons from
other molecules, play a major role in mediating a variety of human disorders. The source of …

Epidemiologic and occupational studies indicate adverse health effects due to inhalation of
particulate air pollutants, but precise biologic mechanisms responsible have yet to be fully …