Oxidative stress in reproduction: a mitochondrial perspective

A Almansa-Ordonez, R Bellido, R Vassena… - Biology, 2020 - mdpi.com
Mitochondria are fundamental organelles in eukaryotic cells that provide ATP through
oxidative phosphorylation. During this process, reactive oxygen species (ROS) are …

Mitochondrial functionality in reproduction: from gonads and gametes to embryos and embryonic stem cells

J Ramalho-Santos, S Varum, S Amaral… - Human reproduction …, 2009 - academic.oup.com
BACKGROUND Mitochondria are multitasking organelles involved in ATP synthesis,
reactive oxygen species (ROS) production, calcium signalling and apoptosis; and …

[HTML][HTML] Impact of oxidative stress on male and female germ cells: implications for fertility

RJ Aitken - Reproduction, 2020 - rep.bioscientifica.com
Male and female germ lines are vulnerable to oxidative stress. In spermatozoa, such stress
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …

Mechanisms of mitochondrial ROS production in assisted reproduction: the known, the unknown, and the intriguing

JN Cobley - Antioxidants, 2020 - mdpi.com
The consensus that assisted reproduction technologies (ART), like in vitro fertilization, to
induce oxidative stress (ie, the known) belies how oocyte/zygote mitochondria—a major …

Oxidative stress and redox regulation of gametogenesis, fertilization, and embryonic development

S Tsunoda, N Kimura, J Fujii - Reproductive medicine and biology, 2014 - Springer
Oxidative stress caused by elevated reactive oxygen species (ROS) is one of the
predominant causes of both male and female infertility. Oxidative stress conditions cause …

Embryo development is impaired by sperm mitochondrial-derived ROS

Y Mateo-Otero, M Llavanera, M Torres-Garrido… - Biological Research, 2024 - Springer
Background Basal energetic metabolism in sperm, particularly oxidative phosphorylation, is
known to condition not only their oocyte fertilising ability, but also the subsequent embryo …

Embryo and its mitochondria

P May-Panloup, M Boguenet, H El Hachem, PE Bouet… - Antioxidants, 2021 - mdpi.com
The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

Oxidative stress and reproductive function: The impact of oxidative stress on reproduction: A focus on gametogenesis and fertilization

RJ Aitken, EG Bromfield, Z Gibb - Reproduction, 2022 - rep.bioscientifica.com
In brief Many aspects of the reproductive process are impacted by oxidative stress. This
article summarizes the chemical nature of reactive oxygen species and their role in both the …

Oxidative stress and assisted reproduction: a comprehensive review of its pathophysiological role and strategies for optimizing embryo culture environment

A Agarwal, I Maldonado Rosas, C Anagnostopoulou… - Antioxidants, 2022 - mdpi.com
Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and
antioxidants has been established as an important factor that can negatively affect the …

Oxidative stress and its role in female infertility and assisted reproduction: clinical implications

A Ashok, S Gupta, N Malhotra, D Sharma - International Journal of Fertility and …, 2009 - ijfs.ir
Reactive oxygen species (ROS) are involved in physiological functions and act as mediators
in various signaling processes. Elevated or sustained generation of free radicals and non …