Natural products (NPs) have been used as traditional medicines since antiquity. With more
than 1060 estimated compounds with molecular weights less than 500 Da representing …

Through evolution, nature has provided natural products (NPs) as a rich source of diverse
bioactive material. Many drug discovery programs have used nature as an inspiration for the …

Nature is considered a prolific source of diverse biologically active chemotypes. While most
reviews have focused on the characteristics of the chemical backbones of natural products …

Small-molecule natural products (NPs) have a long and successful track record of providing
first-in-class drugs and pharmacophore (scaffolds) in all therapeutic areas, serving as a …

The importance of natural products in the treatment of human disease is well documented.
While natural products continue to have a profound impact on human health, chemists have …

Natural products (NPs) are secondary metabolites produced and used by organisms for
defending or adapting purposes. These molecules were naturally selected during thousands …

Over the past two decades natural products drug discovery has been increasingly de-
emphasized by pharmaceutical companies. Although heralded on the verge of a comeback …

Natural products (NPs) have consistently played a pivotal role in pharmaceutical research,
exerting profound impacts on the treatment of human diseases. A significant proportion of …

Context: In recent decades, natural products have undisputedly played a leading role in the
development of novel medicines. Yet, trends in the pharmaceutical industry at the level of …

Historically, most drugs have been derived from natural products, but there has been a shift
away from their use with the increasing predominance of molecular approaches to drug …