In the premature infant, hypoxic-ischemic damage to the cerebral white matter
[periventricular leukomalacia (PVL)] is a common and leading cause of brain injury that often …

Hypoxia-ischemia (HI) is a leading cause of white matter damage, a major contributor to
cerebral palsy in premature infants. Preferential white matter damage is believed to result …

Hypoxic-ischemic injury to the periventricular cerebral white matter [periventricular
leukomalacia (PVL)] results in cerebral palsy and is the leading cause of brain injury in …

Emerging evidence supports that premature infants are susceptible to both cerebral white
and gray matter injury. In a fetal rabbit model of placental insufficiency, preterm rabbits at …

Objective Abnormal myelination is a major pathological sequela of chronic periventricular
white matter injury in survivors of premature birth. We tested the hypothesis that myelination …

Neonatal hypoxia-ischemia in the preterm human leads to selective injury to the subcortical
developing white matter, which results in periventricular leukomalacia (PVL), a condition …

In the immature human brain, periventricular leukomalacia (PVL) is the predominant white
matter injury underlying the development of cerebral palsy. PVL has its peak incidence …

Periventricular white matter injury has a high incidence, particularly in the premature infant.
A prominent feature of the pathogenesis of this injury, which ultimately results in disrupted …

Injury to the preterm brain has a particular predilection for cerebral white matter. White
matter injury (WMI) is the most common cause of brain injury in preterm infants and a major …

Periventricular leukomalacia is the predominant injury in the preterm infant leading to
cerebral palsy. Oxygen exposure may be an additional cause of brain injury in these infants …