Since the earliest descriptions of pain related to injury of the nervous system, it has been
recognized that the characteristics of this type of pain differ markedly from those of pain due …

Many investigators have tried to establish the prevalence of neuropathic pain in the general
population; however, the estimates vary greatly (from 0.9% to 17.9%)[1] according to the …

The past decade has seen great progress in understanding its causes and in finding new
drugs that promise great benefit. An early outcome of the research has been the observation …

Neuropathic pain is a common symptom associated with peripheral neuropathy and can be
as or more disabling than the effects of nerve damage from the neuropathy. Though …

Chronic pain may sometimes be" nociceptive," resulting from ongoing injury to skin, bone, or
viscera. In other cases, pain appears to be sustained by aberrant somatosensory processing …

■ ABSTRACT At long last, advances have been made in the field of neuropathic pain
treatment, in large part due to a better understanding of the mechanisms underlying this type …

Pain usually occurs when a potential tissue-damaging stimulus excites peripheral
nociceptive afferents. When a noxious stimulus activates receptors in skin, muscle, or joint …

Neuropathic pain syndromes, ie, pain after a lesion or disease of the peripheral or central
nervous system, are clinically characterized by spontaneous pain (ongoing, paroxysms) and …

Research on the pathophysiology of chronic pain has begun to challenge the traditional
diagnostic and treatment paradigms for the patient with neuropathic pain. The …

Nociceptive pain alerts the body to potential or actual tissue damage. By contrast,
neuropathic pain, which results from injury or damage to the nervous system, persists long …