The effect of a bacteriophage on diversification of the opportunistic bacterial pathogen, Pseudomonas aeruginosa
MA Brockhurst, A Buckling… - Proceedings of the …, 2005 - royalsocietypublishing.org
Pseudomonas aeruginosa is an opportunistic human pathogen that colonizes the lungs of
cystic fibrosis (CF) patients. CF lungs often contain a diverse range of P. aeruginosa …
cystic fibrosis (CF) patients. CF lungs often contain a diverse range of P. aeruginosa …
Polylysogeny magnifies competitiveness of a bacterial pathogen in vivo
N Burns, CE James, E Harrison - Evolutionary applications, 2015 - Wiley Online Library
The rise of next generation sequencing is revealing a hidden diversity of temperate phages
within the microbial community. While a handful of these phages have been well …
within the microbial community. While a handful of these phages have been well …
Cystic Fibrosis-Niche Adaptation of Pseudomonas aeruginosa Reduces Virulence in Multiple Infection Hosts
The opportunistic pathogen Pseudomonas aeruginosa is able to thrive in diverse ecological
niches and to cause serious human infection. P. aeruginosa environmental strains are …
niches and to cause serious human infection. P. aeruginosa environmental strains are …
Evolutionary diversification of Pseudomonas aeruginosa in an artificial sputum model
Background During chronic lung infections of cystic fibrosis patients Pseudomonas
aeruginosa populations undergo extensive evolutionary diversification. However, the …
aeruginosa populations undergo extensive evolutionary diversification. However, the …
Rapid diversification of Pseudomonas aeruginosa in cystic fibrosis lung-like conditions
Chronic infection of the cystic fibrosis (CF) airway by the opportunistic pathogen
Pseudomonas aeruginosa is the leading cause of morbidity and mortality for adult CF …
Pseudomonas aeruginosa is the leading cause of morbidity and mortality for adult CF …
Temperate phages both mediate and drive adaptive evolution in pathogen biofilms
EV Davies, CE James, D Williams… - Proceedings of the …, 2016 - National Acad Sciences
Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived
sequences are more common in pathogenic than nonpathogenic taxa and are associated …
sequences are more common in pathogenic than nonpathogenic taxa and are associated …
The role of multispecies social interactions in shaping Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lung
S O'Brien, JL Fothergill - FEMS microbiology letters, 2017 - academic.oup.com
Pseudomonas aeruginosa is a major pathogen in the lungs of cystic fibrosis (CF) patients.
However, it is now recognised that a diverse microbial community exists in the airways …
However, it is now recognised that a diverse microbial community exists in the airways …
Characterization of JG024, a Pseudomonas aeruginosa PB1-like broad host range phage under simulated infection conditions
J Garbe, A Wesche, B Bunk, M Kazmierczak… - BMC microbiology, 2010 - Springer
Background Pseudomonas aeruginosa causes lung infections in patients suffering from the
genetic disorder Cystic Fibrosis (CF). Once a chronic lung infection is established, P …
genetic disorder Cystic Fibrosis (CF). Once a chronic lung infection is established, P …
Phenotypic Heterogeneity of Pseudomonas aeruginosa Populations in a Cystic Fibrosis Patient
ML Workentine, CD Sibley, B Glezerson, S Purighalla… - PloS one, 2013 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lower airways
of patients with cystic fibrosis. Throughout the course of infection this organism undergoes …
of patients with cystic fibrosis. Throughout the course of infection this organism undergoes …
Molecular Epidemiology and Dynamics of Pseudomonas aeruginosa Populations in Lungs of Cystic Fibrosis Patients
L Jelsbak, HK Johansen, AL Frost… - Infection and …, 2007 - Am Soc Microbiol
The ability to establish lifelong persistent infections is a fundamental aspect of the
interactions between many pathogenic microorganisms and their mammalian hosts. One …
interactions between many pathogenic microorganisms and their mammalian hosts. One …