Experimental therapy using interferon-gamma and anti-Fas antibody against oral malignant melanoma cells
T Kamei, M Inui, M Nakase, S Nakamura… - Melanoma …, 2005 - journals.lww.com
Abstract The Fas/FasL signalling system plays an important role in chemotherapy-induced
apoptosis in several different cell types. After interferon-gamma (IFN-γ) treatment, we have …
apoptosis in several different cell types. After interferon-gamma (IFN-γ) treatment, we have …
The immune modulation role of low dosage of cyclosporin-A (ldCSA) in the antitumor response of CD8+ T lymphocytes (CD8+ Tcells) and the implication of neuropilin …
Background: The involvement of Nrp1 in the formation of the immunological synapse was
first described by our research team, when demonstrating an increased expression of Nrp1 …
first described by our research team, when demonstrating an increased expression of Nrp1 …
[引用][C] Role of toll-like receptors and nod-like receptors in the antitumor immune response to chemotherapy
C Ortiz-Oliva - 2009
Retinoic acid morpholine amide (RAMA) inhibits expression of Fas ligand through EP1 receptor in colon cancer cells
SX Chen, SY Du, YT Wang, HC Zhao, YL Zhang, L Yao - Tumor Biology, 2016 - Springer
Among the members of tumour necrosis factor family Fas ligand on binding to its receptor
strongly induces apoptosis of tumour-infiltrating lymphocytes (TIL). Thus, FasL acts as an …
strongly induces apoptosis of tumour-infiltrating lymphocytes (TIL). Thus, FasL acts as an …
Effects of high-dose IFNα2b on regional lymph node metastases of human melanoma: modulation of STAT5, FOXP3, and IL-17
W Wang, HD Edington, UNM Rao, DM Jukic… - Clinical Cancer …, 2008 - AACR
Purpose: Signal transducer and activator of transcription 5 (STAT5) and STAT3 oppose one
another in regulation of the reciprocal development of CD4+ CD25+ FOXP3+ regulatory T …
another in regulation of the reciprocal development of CD4+ CD25+ FOXP3+ regulatory T …
Efeitos dos inibidores de IDO e TDO na proliferação, migração e invasão de melanomas humanos e na atividade tumoricida de células mononucleares
MSF Branquinho - 2015 - teses.usp.br
No câncer, o aumento da expressão das enzimas indolamina 2, 3-dioxigenase 1 (IDO1) e
triptofano 2, 3-dioxigenase (TDO), que convertem o triptofano (Trp) em quinurenina (QUIN) …
triptofano 2, 3-dioxigenase (TDO), que convertem o triptofano (Trp) em quinurenina (QUIN) …
[HTML][HTML] Intratumoral CD4+ T lymphodepletion sensitizes poorly immunogenic melanomas to immunotherapy with an OX40 agonist
S Fujiwara, H Nagai, N Shimoura, S Oniki… - Journal of Investigative …, 2014 - Elsevier
Previous studies have shown that the antitumor effects of OX40 agonists depend on the
immunogenicity of the tumor and that poorly immunogenic tumors such as B16F10 …
immunogenicity of the tumor and that poorly immunogenic tumors such as B16F10 …
[PDF][PDF] Research Article Intratumoral TLR-4 Agonist Injection Is Critical for Modulation of Tumor Microenvironment and Tumor Rejection
FLDM Maito, APD de Souza, L Pereira, M Smithey… - 2012 - academia.edu
The tumor microenvironment shelters a complex network of mechanisms that enables local
Immunosuppression to support tumor growth. In this study we found that, B16F10 melanoma …
Immunosuppression to support tumor growth. In this study we found that, B16F10 melanoma …
[PDF][PDF] Efeito da inibição da atividade de ácido graxo sintase (FASN) com cerulenina sobre proliferação e morte de células derivadas de carcinomas espinocelulares …
LR Spada - 2012 - repositorio.unicamp.br
RESUMO A enzima ácido graxo sintase (FASN) desempenha papel chave na lipogênese
de células neoplásicas e está altamente expressa em vários tumores malignos humanos …
de células neoplásicas e está altamente expressa em vários tumores malignos humanos …