Hope and hype around immunotherapy in triple-negative breast cancer

F Jacobs, E Agostinetto, C Miggiano, R De Sanctis… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is the most aggressive breast cancer
subtype accounting for approximately 10–20% of all cases. Due to a lack of actionable …

Immunotherapy in triple negative breast cancer: beyond checkpoint inhibitors

Y Abdou, A Goudarzi, JX Yu, S Upadhaya… - NPJ Breast …, 2022 - nature.com
The development of immunotherapy agents has revolutionized the field of oncology. The
only FDA-approved immunotherapeutic approach in breast cancer consists of immune …

Progress and pitfalls in the use of immunotherapy for patients with triple negative breast cancer

E Agostinetto, A Losurdo, G Nader-Marta… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Triple negative breast cancer (TNBC) is an area of high unmet medical need in
terms of new effective treatment strategies. Although breast cancer is traditionally …

Immunotherapy for triple-negative breast cancer: combination strategies to improve outcome

L Li, F Zhang, Z Liu, Z Fan - Cancers, 2023 - mdpi.com
Simple Summary For decades, countless efforts have been devoted to developing targeted
drugs to improve the prognosis of triple-negative breast cancer (TNBC). Among the novel …

Progress and prospect of immunotherapy for triple-negative breast cancer

C Luo, P Wang, S He, J Zhu, Y Shi, J Wang - Frontiers in Oncology, 2022 - frontiersin.org
Breast cancer is the most commonly diagnosed cancer (estimated 2.3 million new cases in
2020) and the leading cause of cancer death (estimated 685,000 deaths in 2020) in women …

Immunotherapy treatment for triple negative breast cancer

ER Berger, T Park, A Saridakis, M Golshan… - Pharmaceuticals, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is considered one of the highest-risk subtypes of
breast cancer and has dismal prognosis. Local recurrence rate after standard therapy in the …

Combination immunotherapy strategies for triple-negative breast cancer: current progress and barriers within the pharmacological landscape

J Uliano, E Nicolò, C Corvaja… - Expert Review of …, 2022 - Taylor & Francis
Introduction Triple-negative breast cancer (TNBC) is a breast cancer subtype characterized
by poorer prognosis. Despite that TNBC can display immunogenic features, anti-PD (L) 1 …

Immune checkpoint inhibitors in triple negative breast cancer: the search for the optimal biomarker

S Qureshi, N Chan, M George, S Ganesan… - Biomarker …, 2022 - journals.sagepub.com
Triple negative breast cancer (TNBC) is a high-risk and aggressive malignancy
characterized by the absence of estrogen receptors (ER) and progesterone receptors (PR) …

Clinical trials of immunotherapy in triple-negative breast cancer

FM Howard, AT Pearson, R Nanda - Breast Cancer Research and …, 2022 - Springer
Purpose Immunotherapy has started to transform the treatment of triple-negative breast
cancer (TNBC), in part due to the unique immunogenicity of this breast cancer subtype. This …

Immunotherapy in triple-negative breast cancer: Insights into tumor immune landscape and therapeutic opportunities

R Ribeiro, MJ Carvalho, J Goncalves… - Frontiers in Molecular …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer that
represents 15–20% of breast tumors and is more prevalent in young pre-menopausal …