Tumor necrosis factor alpha (TNF alpha) is a central mediator of the immunological
response and the location of the gene within the major histocompatibility complex (MHC) …

Since the tumor necrosis factor alpha (TNF-α) gene was found to be located in the central
major histocompatibility complex (MHC) there has been much speculation concerning a …

Abstract A biallelic G (TNF1 allele) to A (TNF2 allele) polymorphism 308 nucleotides
upstream from the transcription initiation site in the tumor necrosis factor (TNF) promoter is …

Since a dysregulated synthesis of tumor necrosis factor alpha (TNF-alpha) may be involved
in the pathogenesis of autoimmune diseases, it was of interest to precisely locate the …

Tumor necrosis factor α (TNFα) is a potent immunomodulator and proinflammatory cytokine
that has been implicated in the pathogenesis of autoimmune and infectious diseases. For …

Tumor necrosis factor alpha (TNF-α) promoter polymorphisms have been linked to a large
number of diseases but studies examining the possible direct functional effects of these …

Tumor necrosis factor-alpha (TNF-α) is a potent immunomediator and proinflammatory
cytokine that has been implicated in the pathogenesis of a large number of human diseases …

The tumor necrosis factor (TNF) alpha gene lies within the class III region of the major
histocompatibility complex (MHC), telomeric to the class II and centromeric to the class I …

Tumor necrosis factor (TNF) is recognized as a central mediator of sepsis, septic shock, and
multiple organ failure. These host reactions are associated with increased TNF levels in …

Tumor necrosis factor α (TNFα) is a potent inflammatory cytokine. In human, the TNFα gene
is located within the highly polymorphic major histocompatibility complex (MHC) region on …