Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations
O Le Rouzic, M Pichavant, E Frealle… - European …, 2017 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the
airways caused mainly by cigarette smoke exposure. COPD progression is marked by …
airways caused mainly by cigarette smoke exposure. COPD progression is marked by …
Preclinical studies and the function of IL-17 cytokines in COPD
F Ritzmann, C Beisswenger - Annals of Anatomy-Anatomischer Anzeiger, 2021 - Elsevier
Chronic obstructive pulmonary disease (COPD) is among the leading causes of death
worldwide and imposes a high economic burden to the health systems. COPD is …
worldwide and imposes a high economic burden to the health systems. COPD is …
[HTML][HTML] Emerging biological functions of IL-17A: a new target in chronic obstructive pulmonary disease?
M Liu, K Wu, J Lin, Q Xie, Y Liu, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that
causes high rates of disability and mortality worldwide because of severe progressive and …
causes high rates of disability and mortality worldwide because of severe progressive and …
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
MR Starkey, MW Plank, P Casolari… - European …, 2019 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and
death globally. The lack of effective treatments results from an incomplete understanding of …
death globally. The lack of effective treatments results from an incomplete understanding of …
[HTML][HTML] IL-17 cytokines and chronic lung diseases
IL-17 cytokines are expressed by numerous cells (eg, gamma delta (γδ) T, innate lymphoid
(ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the …
(ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the …
T helper 17 cells in airway diseases: from laboratory bench to bedside
R Halwani, S Al-Muhsen, Q Hamid - Chest, 2013 - Elsevier
T helper 17 (Th17) cytokines are now widely believed to be critical for the regulation of
various chronic immune diseases. Investigations have revealed a significant role for IL-17 …
various chronic immune diseases. Investigations have revealed a significant role for IL-17 …
IL-17 in chronic obstructive pulmonary disease
M Cazzola, MG Matera - Expert review of respiratory medicine, 2012 - Taylor & Francis
Th17 cells are a critical component of the adaptive immune response and have also been
implicated in chronic inflammatory diseases and autoimmune diseases [1], although their …
implicated in chronic inflammatory diseases and autoimmune diseases [1], although their …
[HTML][HTML] Role of th17 cell and autoimmunity in chronic obstructive pulmonary disease
SC Hong, SH Lee - Immune network, 2010 - ncbi.nlm.nih.gov
The molecular mechanisms involved in the pathogenesis of chronic obstructive pulmonary
disease (COPD) are poorly defined. Accumulating evidences indicate that chronic …
disease (COPD) are poorly defined. Accumulating evidences indicate that chronic …
A tale of two cytokines: IL-17 and IL-22 in asthma and infection
ML Manni, KM Robinson, JF Alcorn - Expert review of respiratory …, 2014 - Taylor & Francis
The Th17 pathway has recently been shown to play a critical role in host defense, allergic
responses and autoimmune inflammation. Th17 cells predominantly produce IL-17 and IL …
responses and autoimmune inflammation. Th17 cells predominantly produce IL-17 and IL …
Th17 profile in COPD exacerbations
MA Ponce-Gallegos, A Ramírez-Venegas… - … Journal of Chronic …, 2017 - Taylor & Francis
COPD is characterized by an ongoing inflammatory process of the airways that leads to
obstruction or limitation of airflow. It is mainly associated with exposure to cigarette smoke. In …
obstruction or limitation of airflow. It is mainly associated with exposure to cigarette smoke. In …