Multiple biological, behavioural and genetic determinants or correlates of obesity have been
identified to date. Genome-wide association studies (GWAS) have contributed to the …

Obesity is a complex and multifactorial disease that occurs as a result of the interaction
between “obesogenic” environmental factors and genetic components. Although the genetic …

The last few years have seen major advances in common non-syndromic obesity research,
much of it the result of genetic studies. This Review outlines the competing hypotheses …

Candidate gene and genome-wide association studies have led to the discovery of nine loci
involved in Mendelian forms of obesity and 58 loci contributing to polygenic obesity. These …

Obesity and related complications are major health burdens. Almost 700 million adults are
currently obese globally and the prevalence is predicted to rise towards 2030. The sudden …

The prevalence of obesity has tripled over the past four decades, imposing an enormous
burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset …

Obesity is a major public health problem with a significant genetic component. Multiple DNA
polymorphisms/genes have been shown to be strongly associated with obesity, typically in …

It has long been known that there is a genetic component to obesity, and that characterizing
this underlying factor would likely offer the possibility of better intervention in the future …

Obesity is a major public health concern. This condition results from a constant and complex
interplay between predisposing genes and environmental stimuli. Current attempts to …

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