Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

A brief history of oxytocin and its role in modulating psychostimulant effects

DS Carson, AJ Guastella, ER Taylor… - Journal of …, 2013 - journals.sagepub.com
Over the past century, the polypeptide oxytocin has played an important role in medicine
with major highlights including the identification of its involvement in parturition and the milk …

Targeting the oxytocin system: new pharmacotherapeutic approaches

D Gulliver, E Werry, TA Reekie, TA Katte… - Trends in …, 2019 - cell.com
Deficits in social behavioral domains, such as interpersonal communication, emotion
recognition, and empathy, are a characteristic symptom in several neuropsychiatric …

Molecular basis of oxytocin receptor signalling in the brain: what we know and what we need to know

M Busnelli, B Chini - Behavioral pharmacology of neuropeptides: Oxytocin, 2018 - Springer
Oxytocin (OT), a hypothalamic neuropeptide involved in regulating the social behaviour of
all vertebrates, has been proposed as a treatment for a number of neuropsychiatric …

From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders

A Romano, B Tempesta… - Frontiers in …, 2016 - frontiersin.org
Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and
supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a …

Oxytocin in the socioemotional brain: implications for psychiatric disorders

P Kirsch - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
The neuropeptide oxytocin (OXT), highly conserved during evolution, is an important
modulator of social and emotional processes across many species. During the last decade …

Overview of human oxytocin research

KM Kendrick, AJ Guastella, B Becker - Behavioral pharmacology of …, 2018 - Springer
Social dysfunction is a core symptom of many psychiatric disorders and current medications
have little or no remedial effects on this. Following on from extensive studies on animal …

Fear-enhancing effects of septal oxytocin receptors

YF Guzmán, NC Tronson, V Jovasevic, K Sato… - Nature …, 2013 - nature.com
The nonapeptide oxytocin is considered beneficial to mental health due to its anxiolytic,
prosocial and antistress effects, but evidence for anxiogenic actions of oxytocin in humans …

Stimuli and consequences of dendritic release of oxytocin within the brain

ID Neumann - Biochemical Society Transactions, 2007 - portlandpress.com
The brain oxytocin system has served as a distinguished model system in
neuroendocrinology to study detailed mechanisms of intracerebral release, in particular of …

Oxytocin: crossing the bridge between basic science and pharmacotherapy

C Viero, I Shibuya, N Kitamura… - CNS neuroscience & …, 2010 - Wiley Online Library
Is oxytocin the hormone of happiness? Probably not. However, this small nine amino acid
peptide is involved in a wide variety of physiological and pathological functions such as …