Association of tumor necrosis factor polymorphism with primary sclerosing cholangitis

W Bernal, M Moloney, J Underhill, PT Donaldson - Journal of hepatology, 1999 - Elsevier
Background/Aims: Primary sclerosing cholangitis is associated with the HLA haplotypes A1-
B8-DRB3* 0101-DRB1* 0301-DQA1* 0501-DQB1* 0201 and DRB3* 0101-DRB1* 1301 …

Association of the tumour necrosis factor α− 308 but not the interleukin 10− 627 promoter polymorphism with genetic susceptibility to primary sclerosing cholangitis

SA Mitchell, J Grove, A Spurkland, KM Boberg… - Gut, 2001 - gut.bmj.com
BACKGROUND AND AIMS Primary sclerosing cholangitis (PSC) is a chronic cholestatic
liver disease of unknown aetiology. Abnormalities in immune regulation and genetic …

Genetic associations in Italian primary sclerosing cholangitis: heterogeneity across Europe defines a critical role for HLA-C

JR Hov, A Lleo, C Selmi, B Woldseth, L Fabris… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: The HLA complex on chromosome 6p21 is firmly established as a
risk locus for primary sclerosing cholangitis (PSC). We aimed to exploit genetic differences …

Novel association of HLA-haplotypes with primary sclerosing cholangitis (PSC) in a southern European population

TM Neri, GM Cavestro, P Seghini, PF Zanelli… - Digestive and liver …, 2003 - Elsevier
Aims. In patients with with primary sclerosing cholangitis we investigated the major
histocompatibility complex (MHC) genes and mutations of the cystic fibrosis transmembrane …

The interleukin-1 and interleukin-10 gene polymorphisms in primary sclerosing cholangitis: no associations with disease susceptibility/resistance

PT Donaldson, S Norris, PK Constantini, W Bernal… - Journal of …, 2000 - Elsevier
background/aims: although primary sclerosing cholangitis is believed to be an autoimmune
disorder, no tissue-specific auto-antibodies have yet been identified, and the strongest …

HLA DR4 is a marker for rapid disease progression in primary sclerosing cholangitis

WZ Mehal, YMD Lo, BP Wordsworth, JM Neuberger… - Gastroenterology, 1994 - Elsevier
Background/Aims: Primary sclerosing cholangitis (PSC) is an inflammatory disease of the
biliary tree associated with an increase in the HLA alleles DR3, DR52a, DR2, Dw2, and a …

Polymorphisms in tumour necrosis factor α, interleukin-10 and transforming growth factor β1 genes and end-stage liver disease

AJ Bathgate, V Pravica, C Perrey… - European journal of …, 2000 - journals.lww.com
Objective: To determine any relationship between polymorphisms in the genes encoding
tumour necrosis factor [alpha](TNF [alpha]), interleukin-10 (IL-10) and transforming growth …

Primary sclerosing cholangitis is associated with extended HLA‐DR3 and HLA‐DR6 haplotypes

K Wiencke, TH Karlsen, KM Boberg, E Thorsby… - Tissue …, 2007 - Wiley Online Library
Primary sclerosing cholangitis (PSC) is associated with the human leukocyte antigen (HLA)‐
DRB1* 0301‐DQA1* 0501‐DQB1* 0201 (DR3) and HLA‐DRB1* 1301‐DQA1* 0103‐DQB1 …

Susceptibility to primary sclerosing cholangitis in Brazil is associated with HLA-DRB1* 13 but not with tumour necrosis factor α− 308 promoter polymorphism

PL Bittencourt, SA Palacios, ELR Cançado, FJ Carrilho… - Gut, 2002 - gut.bmj.com
If you have a burning desire to respond to a paper published in Gut, why not make use of our
“rapid response” option? Log onto our website (www. gutjnl. com), find the paper that …

Human leukocyte antigen-C genes and susceptibility to primary sclerosing cholangitis

MM Moloney, LJ Thomson, MJ Strettell, R Williams… - Hepatology, 1998 - journals.lww.com
Genetic susceptibility to primary sclerosing cholangitis (PSC) is associated with the
extended HLA A1-B8-DR3 haplotype and also with the DRB3* 0101-DRB1* 0301-DQA1 …