Publisher Summary This chapter explains how sympathetic imaging provides an important
supplement to physiological, neurochemical, and neuropharmacological approaches in the …

Sympathetic neuroimaging provides an important supplement to physiological,
neurochemical, and neuropharmacological approaches in the evaluation of patients with …

OBJECTIVE: The aim of this study was to analyze autonomic function and cardiac
sympathetic innervation in symptomatic and asymptomatic carriers of the E46K alpha …

Introduction Here we report the case of an asymptomatic carrier of the E46K substitution in α-
synuclein gene where we have documented that cardiac sympathetic denervation precedes …

Symptoms or signs of abnormal autonomic nervous system function occur commonly in
several neurological disorders. Clinical evaluations have depended on physiological …

Parkinson's disease patients frequently have symptoms and signs of autonomic nervous
dysfunction that are the source of considerable disability. Recent studies have revealed that …

Introduction Parkinson disease (PD), pure autonomic failure (PAF), and multiple system
atrophy (MSA) are characterized by intra-cerebral deposition of the protein alpha-synuclein …

Objective Lewy body (LB) synucleinopathies such as Parkinson's disease (PD) entail
profound cardiac norepinephrine deficiency. The status of sympathetic noradrenergic …

Sympathetic neuroimaging is based on the injection of compounds that either radiolabel
sites of the cell membrane norepinephrine transporter (NET) or that are taken up into …

Braak's staging concept of Lewy body disease pathogenesis is based on a spatiotemporal
sequence of alpha-synuclein deposition, with autonomic nervous system involvement before …