Clinical and laboratory features of 99 patients receiving long-term amiodarone therapy were
analyzed to determine which individuals may be at a high risk for developing amiodarone …

Amiodarone, a drug that has electrophysiologic actions resembling those of hypothyroidism,
increases serum levels of T 4 and reverse T 3 (rT 3) and decreases T 3. The drug's long-term …

In order to evaluate the effects of amiodarone on thyroid function in chronically treated
patients, 43 consecutive patients, who had been taking a mean weekly dose of 1420±488 …

Both hyperthyroidism and hypothyroidism have been noted to occur in some patients treated
with amiodarone for cardiac arrhythmias. To determine the frequency of the development of …

Amiodarone blocks the action of thyroid hormone by the inhibition of 5′-deiodinase which
reduces production of T 3 in peripheral tissues and possibly by blocking nuclear binding of T …

Objective: To determine whether long-term amiodarone treatment is associated with a rise in
plasma cholesterol, and, if so, to analyze its relation with thyroid function. Design …

Amiodarone, an iodinated benzofuran derivative, has electrophysiologic effects on cardiac
muscle akin to those of hypothyroidism. It is possible that the drug exerts its salutary effect, at …

Purpose: To review the literature on the effects of amiodarone on thyroid physiology and
management of amiodarone-induced thyroid disease. Data Sources: English-language …

Amiodarone has been reported as an anti-anginal drug in 19h7 [11 and as an anti-
arrhythmic drug in 1969 [2]. Thyroid side-effects (hypothyroidism and thyrotoxicosis) were …

Because the value of monitoring amiodarone plasma concentrations remains undefined, this
study was performed to evaluate its role during the management of patients receiving …