Multifunctional Mesoporous Polydopamine‐Based Systematic Delivery of STING Agonist for Enhanced Synergistic Photothermal‐Immunotherapy

W Zeng, Z Li, Q Huang, C Ding, L Yang… - Advanced Functional …, 2024 - Wiley Online Library
The therapeutic application of STING agonists in various malignancies has been limited by
factors such as the inability of systemic administration and the immunosuppressive tumor …

Tumor microenvironment‐responsive delivery nanosystems reverse immunosuppression for enhanced CO gas/immunotherapy

B Chen, K Guo, X Zhao, Z Liu, C Xu, N Zhao… - Exploration, 2023 - Wiley Online Library
Carbon monoxide (CO) gas therapy demonstrates great potential to induce cancer cell
apoptosis and antitumor immune responses, which exhibits tremendous potential in cancer …

Tumor-homing and immune-reprogramming cellular nanovesicles for photoacoustic imaging-guided phototriggered precise chemoimmunotherapy

Z Fan, Y Wang, L Li, F Zeng, Q Shang, Y Liao… - ACS …, 2022 - ACS Publications
Many studies have focused on developing effective therapeutic strategies to selectively
destroy primary tumors, eliminate metastatic lesions, and prevent tumor recurrence with …

Neutrophil delivered hollow titania covered persistent luminescent nanosensitizer for ultrosound augmented chemo/immuno glioblastoma therapy

Y Li, X Teng, Y Wang, C Yang, X Yan, J Li - Advanced science, 2021 - Wiley Online Library
Glioblastoma (GBM) is the most malignant brain tumor with unmet therapeutic demand. The
blood‐brain‐barrier (BBB) and tumor heterogeneity limit the treatment effectiveness of …

Manganese Dioxide-Entrapping Dendrimers Co-Deliver Protein and Nucleotide for Magnetic Resonance Imaging-Guided Chemodynamic/Starvation/Immune Therapy …

Y Gao, Z Ouyang, S Shen, H Yu, B Jia, H Wang… - ACS …, 2023 - ACS Publications
Development of a nanoscale drug delivery system that can simultaneously exert efficient
tumor therapeutic efficacy while creating the desired antitumor immune responses is still …

An Intelligent Biomimetic Nanoplatform for Holistic Treatment of Metastatic Triple-Negative Breast Cancer via Photothermal Ablation and Immune Remodeling

Y Cheng, Q Chen, Z Guo, M Li, X Yang, G Wan… - ACS …, 2020 - ACS Publications
Metastasis is one of the main causes of failure in the treatment of triple-negative breast
cancer (TNBC). Immunotherapy brings hope and opportunity to solve this challenge, while …

Self-assembled minimalist multifunctional theranostic nanoplatform for magnetic resonance imaging-guided tumor photodynamic therapy

H Zhang, K Liu, S Li, X Xin, S Yuan, G Ma, X Yan - ACS nano, 2018 - ACS Publications
Minimalist multifunctional platforms for delivering diagnostic and therapeutic agents
effectively and safely into tumor sites are highly desired in nanomedicine. Herein, we …

Dual-responsive triple-synergistic Fe-MOF for tumor theranostics

Z Chen, Y Sun, J Wang, X Zhou, X Kong, J Meng… - ACS …, 2023 - ACS Publications
The intelligent responsive drug delivery system has great application potential in cancer
precision therapy. Although many antitumor methods have been developed based on drug …

A nanoarchitectonic approach enables triple modal synergistic therapies to enhance antitumor effects

Z Mo, Q Li, K Zhao, Q Xu, H Hu, X Chen… - … Applied Materials & …, 2022 - ACS Publications
Improvement of antitumor effects relies on the development of biocompatible nanomaterials
and combination of various therapies to produce synergistic effects and avoid resistance. In …

Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy

C Xu, F Chen, HF Valdovinos, D Jiang, S Goel, B Yu… - Biomaterials, 2018 - Elsevier
Mesoporous silica nanoshell (MSN) coating has been demonstrated as a versatile surface
modification strategy for various kinds of inorganic functional nanoparticles, such as gold …