Detection of RET rearrangements in papillary thyroid carcinoma using RT-PCR and FISH techniques-a molecular and clinical analysis
TJ Musholt, JI Staubitz, RJA Cámara… - European Journal of …, 2019 - Elsevier
Abstract Introduction Oncogenic BRAF and RAS mutations as well as multiple known (and
yet unknown) RET fusion oncogenes comprise the majority of causative molecular …
yet unknown) RET fusion oncogenes comprise the majority of causative molecular …
Molecular pathogenesis of pediatric thyroid carcinoma
N Mitsutake, V Saenko - Journal of radiation research, 2021 - academic.oup.com
There has been little understanding of the molecular pathogenesis of pediatric thyroid
cancers. Most of them are histologically classified as papillary thyroid carcinoma (PTC) …
cancers. Most of them are histologically classified as papillary thyroid carcinoma (PTC) …
Familial vs sporadic papillary thyroid carcinoma: a matched-case comparative study showing similar clinical/prognostic behaviour
AE Pinto, GL Silva, R Henrique… - European journal of …, 2014 - academic.oup.com
Objective Familial non-medullary thyroid cancer has been proposed as an aggressive
clinical entity. Our aim in this study is to investigate potential distinguishing features as well …
clinical entity. Our aim in this study is to investigate potential distinguishing features as well …
Approach to risk stratification for papillary thyroid carcinoma based on molecular profiling: institutional analysis
JI Staubitz, C Müller, A Heymans, C Merten, B Roos… - BJS open, 2023 - academic.oup.com
Background Currently, treatment recommendations for papillary thyroid carcinoma are not
based on the genetic background causing tumourigenesis. The aim of the present study was …
based on the genetic background causing tumourigenesis. The aim of the present study was …
[HTML][HTML] Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs infiltrative) reveals distinct BRAF …
M Rivera, J Ricarte-Filho, J Knauf, A Shaha, M Tuttle… - Modern pathology, 2010 - Elsevier
The follicular variant of papillary thyroid carcinoma usually presents as an encapsulated
tumor and less commonly as a partially/non-encapsulated infiltrative neoplasm. The …
tumor and less commonly as a partially/non-encapsulated infiltrative neoplasm. The …
Is multifocality a predictor of poor outcome in childhood and adolescent papillary thyroid carcinoma?
DW Scholfield, J Lopez, A Eagan, Z Antal… - The Journal of …, 2023 - academic.oup.com
Context Total thyroidectomy in pediatric papillary thyroid carcinoma (PTC) is recommended
in national guidelines because of the high incidence of multifocal disease (MFD). Objective …
in national guidelines because of the high incidence of multifocal disease (MFD). Objective …
A detailed histologic and molecular assessment of the diffuse sclerosing variant of papillary thyroid carcinoma
Diffuse sclerosing variant papillary thyroid carcinoma (DS-PTC) is characterized clinically by
a predilection for children and young adults, bulky neck nodes, and pulmonary metastases …
a predilection for children and young adults, bulky neck nodes, and pulmonary metastases …
RET rearrangements and BRAF mutation in undifferentiated thyroid carcinomas having papillary carcinoma components
K Mochizuki, T Kondo, T Nakazawa, M Iwashina… - …, 2010 - Wiley Online Library
Mochizuki K, Kondo T, Nakazawa T, Iwashina M, Kawasaki T, Nakamura N, Yamane T,
Murata S‐i, Ito K, Kameyama K, Kobayashi M & Katoh R (2010) Histopathology 57, 444–450 …
Murata S‐i, Ito K, Kameyama K, Kobayashi M & Katoh R (2010) Histopathology 57, 444–450 …
Impact of mutation density and heterogeneity on papillary thyroid cancer clinical features and remission probability
C Colombo, M Muzza, MC Proverbio, D Tosi… - Thyroid, 2019 - liebertpub.com
Background: The need to integrate the classification of cancer with information on the
genetic pattern has emerged in recent years for several tumors. Methods: The genomic …
genetic pattern has emerged in recent years for several tumors. Methods: The genomic …
[HTML][HTML] Multi-gene assay and clinical characteristics research in papillary thyroid carcinoma
C Deng, S Li, Z Yang, Y Dou, D Hu, J Zhu, D Wang… - Gland …, 2021 - ncbi.nlm.nih.gov
Background To investigate the significance of multi-gene assay in papillary thyroid
carcinoma (PTC) patients in clinical practice. Methods From April to December 2019 …
carcinoma (PTC) patients in clinical practice. Methods From April to December 2019 …