Peppermint oil (Mentha× piperita L.(Lamiaceae) has been shown to exert potent antiemetic
properties, but its mode of action has not yet been elucidated. Among its active constituents …

The effects of alcohol monoterpene menthol, a major active ingredient of the peppermint
plant, were tested on the function of human 5-hydroxytryptamine type 3 (5-HT3) receptors …

A contribution of the volatile oil from ginger rhizomes (Zingiber officinale Roscoe) on
inhibiting the 5-HT 3 receptor complex had been shown. In the present study a possible …

Abstract Serotonin receptor type 3 (5-HT 3 receptor) is a ligand-gated ion channel that is
expressed in the central nervous system (CNS) as well as in the peripheral nervous system …

Ginger (rhizomes of Zingiber officinale) has been shown to exert potent anti-emetic
properties, but its mode of action has not yet been elucidated. Among its active …

Clinical studies with the fixed herbal combination product STW 5 (Iberogast®) have
indicated an efficacy comparable to metoclopramide (5-HT3 antagonist) and cisapride (5 …

The primary aim of this investigation was to determine whether binding sites corresponding
to the 5‐HT7 receptor could be detected in smooth muscle of the rat jejunum. Binding …

Different extracts (ethanolic, hexane, aqueous) of ginger (rhizomes of Zingiber officinale)
and the essential oil were tested using [14 C] guanidinium influx into N1E-115 cells and the …

The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of
gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT3 …

Citral, eucalyptol, and linalool are widely used as flavorings, fragrances, and cosmetics.
Here, we examined their effects on electrophysiological and binding properties of human 5 …