Macroautophagy is a degradation/recycling system ubiquitous in eukariotic cells, which
generates nutrients during fasting under the control of amino acids and hormones, and …

In recent years, skin aging has received increasing attention. Many factors affect skin aging,
and research has shown that metabolism plays a vital role in skin aging, but there needs to …

Skin aging is a complex process, and alterations in human skin due to aging have distinct
characteristic as compared to other organs. The aging of dermal cells and the biological …

Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging
and even more for extrinsic aging. Although the results are quite different in dermis and …

Autophagy is a critical quality control pathway that is conserved across diverse systems
ranging from simple unicellular organisms like yeast to more complex systems, for instance …

This contribution will address the effect of aging on skin functions, with a particular focus on
skin permeability, wound healing, angiogenesis, lipogenesis, sweat production, immune …

Cellular senescence and aging result in a reduced ability to manage persistent types of
inflammation. Thus, the chronic low-level inflammation associated with aging phenotype is …

Cellular senescence is an extremely stable form of cell cycle arrest activated in response to
stress. Autophagy, a lysosome-dependent cellular catabolic process, can also be triggered …

The skin is the largest organ and has a key protective role. Similar to any other tissue, the
skin is influenced not only by intrinsic/chronological aging, but also by extrinsic aging …

Autophagy is the central cellular mechanism for delivering organelles and cytoplasm to
lysosomes for degradation and recycling of their molecular components. To determine the …