Autophagy in UV damage response

A Sample, YY He - Photochemistry and photobiology, 2017 - Wiley Online Library
UV radiation exposure from sunlight and artificial tanning beds is the major risk factor for the
development of skin cancer and skin photoaging. UV‐induced skin damage can trigger a …

AGEs induced autophagy impairs cutaneous wound healing via stimulating macrophage polarization to M1 in diabetes

Y Guo, C Lin, P Xu, S Wu, X Fu, W Xia, M Yao - Scientific reports, 2016 - nature.com
Autophagy is essential in physiological and pathological processes, however, the role of
autophagy in cutaneous wound healing and the underlying molecular mechanism remain …

Identification of biomarkers of human skin ageing in both genders. Wnt signalling-a label of skin ageing?

E Makrantonaki, TC Brink, V Zampeli, RM Elewa… - PloS one, 2012 - journals.plos.org
The goal of our work has been to investigate the mechanisms of gender-independent
human skin ageing and examine the hypothesis of skin being an adequate model of global …

[HTML][HTML] Aging Process and Related Diseases

F Taheri, E Rahmani, SS Fard, M Rezaei, A Ayati… - Kindle, 2023 - preferpub.org
The aging process is a complex biological phenomenon that results in the gradual decline of
physiological function and an increased risk of age-related diseases. While aging is a …

Exogenous factors in skin aging

M Landau - Environmental Factors in Skin Diseases, 2007 - karger.com
The dramatic alteration in the appearance of the skin with aging is related to both intrinsic
(genetic) and exogenous factors. While intrinsic aging is an insidious degenerative process …

Macroautophagy and aging: The impact of cellular recycling on health and longevity

JL Nieto-Torres, M Hansen - Molecular aspects of medicine, 2021 - Elsevier
Aging is associated with many deleterious changes at the cellular level, including the
accumulation of potentially toxic components that can have devastating effects on health. A …

Autophagy dysfunction, cellular senescence, and abnormal immune‐inflammatory responses in AMD: From mechanisms to therapeutic potential

S Wang, X Wang, Y Cheng, W Ouyang… - Oxidative medicine …, 2019 - Wiley Online Library
Age‐related macular degeneration (AMD) is a blinding disease caused by multiple factors
and is the primary cause of vision loss in the elderly. The morbidity of AMD increases every …

The skin and inflamm-aging

R Agrawal, A Hu, WB Bollag - Biology, 2023 - mdpi.com
Simple Summary Aging affects all cells of the body, leading to impaired system function.
Although scientists are beginning to identify some mechanisms underlying the aging …

Autophagy in human keratinocytes: an early step of the differentiation?

E Aymard, V Barruche, T Naves… - Experimental …, 2011 - Wiley Online Library
Studies have established that autophagy constitutes an efficient process to recycle cellular
components and certain proteins. The phenomenon was demonstrated primarily in …

Autophagy impairment induces premature senescence in primary human fibroblasts

HT Kang, KB Lee, SY Kim, HR Choi, SC Park - PloS one, 2011 - journals.plos.org
Background Recent studies have demonstrated that activation of autophagy increases the
lifespan of organisms from yeast to flies. In contrast to the lifespan extension effect in lower …