There are specific pharmacology issues related to women's unique physiology, including the
hormonal changes that occur throughout their life span. Studies have shown alterations in …

There is an increasing awareness that the exclusion of women from clinical trials may lead
to inaccurate application of drug therapy in women. Gender and estrus cycle differences in …

There are a number of examples of sex differences in drug pharmacokinetics and
pharmacodynamics. Recent advances in the characterisation of specific isozymes involved …

Significant differences that exist between the sexes affect the prevalence, incidence and
severity of a broad range of diseases and conditions. Men and women also differ in their …

In recent years, it has become clear that women and men may differ for drug response. Also,
there is an increasing recognition on the role of sex hormones on pharmacokinetics and …

Within the field of drug metabolism, when addressing quantitative aspects, an average value
is traditionally quoted, commonly the arithmetic mean with perhaps an indication of spread …

Background: Sex and gender-based differences are observed well beyond the sex organs
and affect several physiological and biochemical processes involved in the metabolism of …

Practitioners are often troubled by the lack of well characterized data on appropriate drug
dosing, on effectiveness of treatment, and on drug safety for women and for women in …

A rough 24-hour cycle driven endogenously in biochemical, physiological or behavioral
processes is called circadian rhythm. Chronobiology is the study of biological temporal …

There are pharmacological differences between women and men that have important
clinical consequences. For several drugs, there is a higher incidence in women of drug …