Abnormal craniofacial bone fusion can lead to the generation of several congenital
malformations such as cleft palate, craniosynostosis and craniofacial skeletal hypoplasia …

Over the past decades, there has been a substantial amount of innovation and research into
tissue engineering and regenerative approaches for the craniofacial region. This highly …

The primary goals of craniofacial reconstruction include the restoration of the form, function,
and facial esthetics, and in the case of pediatric patients, respect for craniofacial growth. The …

Current reconstructive approaches to large craniofacial skeletal defects are often
complicated and challenging. Critical-sized defects are unable to heal via natural …

Craniofacial bone defect anomalies affect both soft and hard tissues and can be caused by
trauma, bone recessions from tumors and cysts, or even from congenital disorders. On this …

The repair of bone defects and nonunions remains a significant clinical problem in
orthopedic and maxillofacial reconstructive surgery. Tissue engineering offers a potential …

Featured Application This review outlines the extant techniques and innovative
biotechnologies to implement the surgical treatment of craniosynostosis and related …

The craniofacial region consists of several different tissue types. These tissues are quite
commonly affected by traumatic/pathologic tissue loss which has so far been traditionally …

Craniofacial reconstruction requires robust bone of specified geometry for the repair to be
both functional and aesthetic. While native bone from elsewhere in the body can be …

Conditions such as congenital anomalies, cancers, and trauma can all result in devastating
deficits of bone in the craniofacial skeleton. This can lead to significant alteration in function …