Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice

A Bellucci, I Luccarini, C Scali, C Prosperi… - Neurobiology of …, 2006 - Elsevier
In 7-month-old TgCRND8 mice, the extracellular cortical acetylcholine levels in vivo, the
number and morphology of cholinergic neurons in the nucleus basalis magnocellularis and …

Atipamezole-precipitated clonidine withdrawal induces c-Fos expression in rat central nervous system

RL Stornetta, MC Grubb, PG Guyenet - Brain research, 1997 - Elsevier
We sought to identify a clonidine withdrawal syndrome in conscious rats by investigating the
effects of a single injection of the specific α2-adrenergic antagonist atipamezole (1.5 mg/kg …

Behavioral sensitization to cocaine after a brief social stress is accompanied by changes in fos expression in the murine brainstem

EM Nikulina, JE Marchand, RM Kream, KA Miczek - Brain research, 1998 - Elsevier
The objective of the present study was to determine how c-fos gene expression in brainstem
structures after a brief episode of social defeat stress is related to behavioral sensitization to …

Characteristic changes of astrocyte and microglia in rat striatum induced by 3-NP and MCAO

S Mu, B Liu, L Ouyang, M Zhan, S Chen, J Wu… - Neurochemical …, 2016 - Springer
Our previous studies had confirmed that both 3-NP and MCAO induced the behavioral
defect as well as striatal neuronal injury and loss in experimental rats. This study aimed to …

Selective destruction of medial septal cholinergic neurons attenuates pyramidal cell suppression, but not excitation in dorsal hippocampus field CA1 induced by …

F Zheng, S Khanna - Neuroscience, 2001 - Elsevier
Using extracellular recording techniques in urethane-(1g/kg, ip) anaesthetized rats, we
investigated the influence exercised by medial septal cholinergic neurons on dorsal …

Neuroprotective effects of donepezil against cholinergic depletion

D Cutuli, P De Bartolo, P Caporali… - Alzheimer's research & …, 2013 - Springer
Introduction Intraparenchymal injections of the immunotoxin 192-IgG-saporin into medial
septum and nucleus basalis magnocellularis causes a selective depletion of basal forebrain …

Molsidomine modulates the cNOS activity in an experimental model of cholinergic damage induced by 192-IgG saporin

MA Hernández-Melesio, D González-Esquivel… - Neuroscience …, 2011 - Elsevier
The aim of this work was to study the effect of molsidomine (MOLS), a nitric oxide (NO)
donor, on the nitrergic system changes in an experimental model of cholinergic damage …

Regional distribution of Fos-like immunoreactivity in the rat brain after exposure to fear-inducing stimuli.

MC Silveira, FG Graeff, G Sandner - Brazilian Journal of Medical and …, 1994 - europepmc.org
Fos protein immunohistochemistry was used to identify the neural substrate of fear/anxiety.
The structures activated by exposure of Long Evans male rats (280-300 g) to the elevated …

Neurochemical and behavioral recovery after colchicine lesions of the nucleus basalis magnocellularis in rats

LW Shaughnessy, S Barone Jr… - Restorative …, 1996 - content.iospress.com
Experimentally-induced lesions of the basal forebrain have been used to test the hypothesis
that the cholinergic system plays a critical role in learning and memory. In the present study …

Enhanced cortical extracellular levels of cholecystokinin-like material in a model of anticipation of social defeat in the rat

C Becker, MH Thiébot, Y Touitou, M Hamon… - Journal of …, 2001 - Soc Neuroscience
The involvement of cholecystokinin (CCK) in the mechanisms of stress and/or anxiety was
assessed by in vivo microdialysis in rats subjected to a social stress paradigm. During the …