Integrated microbiome-metabolomics analysis reveals the potential therapeutic mechanism of Zuo-Jin-Wan in ulcerative colitis

Y Cai, S Li, X Zhang, X Cao, D Liu, Y Zhu, S Ye, Z Xu… - Phytomedicine, 2022 - Elsevier
Background Dysregulation in gut microbiota and host cometabolome contributes to the
complicated pathology of ulcerative colitis (UC), while Zuo-Jin-Wan (ZJW), a traditional …

Lizhong decoction ameliorates ulcerative colitis in mice via modulating gut microbiota and its metabolites

J Zou, Y Shen, M Chen, Z Zhang, S Xiao, C Liu… - Applied Microbiology …, 2020 - Springer
Ulcerative colitis (UC), a kind of inflammatory bowel disease, is generally characterized by
chronic, persistent, relapsing, and nonspecific ulceration of the bowel, which is widespread …

Huangqin decoction ameliorates DSS-induced ulcerative colitis: Role of gut microbiota and amino acid metabolism, mTOR pathway and intestinal epithelial barrier

M Li, M Li, J Lei, Y Wu, Z Li, L Chen, C Zhou, J Su… - Phytomedicine, 2022 - Elsevier
Background The clinical treatment of ulcerative colitis (UC) is limited. A traditional Chinese
medicinal formula, Huangqin decoction (HQD), is chronicled in Shang Han Lun and is …

The pharmacological validation of the Xiao-Jian-Zhong formula against ulcerative colitis by network pharmacology integrated with metabolomics

W Yu, Z Liang, Q Li, Y Liu, X Liu, L Jiang, C Liu… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Inflammatory bowel disease (IBD) is pathologically
characterized by an immune response accommodative insufficiency and dysbiosis …

Integrated network pharmacology and metabolomics reveal the mechanisms of Jasminum elongatum in anti-ulcerative colitis

J Qiu, G Xiao, M Yang, X Huang, D Cai, C Xie… - Scientific Reports, 2023 - nature.com
Jasminum elongatum (JE), an ethnic Chinese medicine, is widely used in the Lingnan
region of China, because of its analgesic and antidiarrheal action, as well as its anti …

Zingiber officinale and Panax ginseng ameliorate ulcerative colitis in mice via modulating gut microbiota and its metabolites

Y Wan, L Yang, H Li, H Ren, K Zhu, Z Dong… - … of Chromatography B, 2022 - Elsevier
Zingiber officinale and Panax ginseng, as well-known traditional Chinese medicines, have
been used together to clinically treat ulcerative colitis with synergistic effects for thousands of …

[HTML][HTML] Therapeutic effects and mechanisms of Zhen-Wu-Bu-Qi Decoction on dextran sulfate sodium-induced chronic colitis in mice assessed by multi-omics …

L Zhai, J Peng, M Zhuang, YY Chang, KW Cheng… - Phytomedicine, 2022 - Elsevier
Abstract Background Zhen-Wu-Bu-Qi Decoction (ZWBQD), a traditional Chinese medicine
formula comprising Poria, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae …

[HTML][HTML] Gut microbiota drives the attenuation of dextran sulphate sodium-induced colitis by Huangqin decoction

Y Yang, G Chen, Q Yang, J Ye, X Cai, P Tsering… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The gut microbiota, including probiotics and pathogenic microorganisms, is involved in
ulcerative colitis (UC) by regulating pathogenic microorganisms and the production of …

The San-Qi-Xue-Shang-Ning formula protects against ulcerative colitis by restoring the homeostasis of gut immunity and microbiota

W Yu, C Kang, Y Zhang, Q Li, Z Zhang, Y Zheng… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Ulcerative colitis (UC) is a major cause of morbidity and
mortality due to repetitive remissions and relapses, and many severe complications …

Kuijieling, a Chinese medicine alleviates DSS-induced colitis in C57BL/6Jmouse by improving the diversity and function of gut microbiota

G Pan, B Liu, S Li, M Han, L Gao, G Xu… - FEMS microbiology …, 2020 - academic.oup.com
Ulcerative colitis (UC) is a gastrointestinal disease. The link between gut microbiota and the
inflammatory response in the gut has been recently established. Restoration of gut …