Deep learning in digital pathology for personalized treatment plans of cancer patients

Z Wen, S Wang, DM Yang, Y Xie, M Chen… - Seminars in diagnostic …, 2023 - Elsevier
Over the past decade, many new cancer treatments have been developed and made
available to patients. However, in most cases, these treatments only benefit a specific …

The future of artificial intelligence in digital pathology–results of a survey across stakeholder groups

CN Heinz, A Echle, S Foersch, A Bychkov… - …, 2022 - Wiley Online Library
Aims Artificial intelligence (AI) provides a powerful tool to extract information from digitised
histopathology whole slide images. During the last 5 years, academic and commercial …

Application of digital pathology‐based advanced analytics of tumour microenvironment organisation to predict prognosis and therapeutic response

X Fu, E Sahai, A Wilkins - The Journal of Pathology, 2023 - Wiley Online Library
In recent years, the application of advanced analytics, especially artificial intelligence (AI), to
digital H&E images, and other histological image types, has begun to radically change how …

Future of biomarker evaluation in the realm of artificial intelligence algorithms: application in improved therapeutic stratification of patients with breast and prostate …

J Fitzgerald, D Higgins, CM Vargas, W Watson… - Journal of Clinical …, 2021 - jcp.bmj.com
Clinical workflows in oncology depend on predictive and prognostic biomarkers. However,
the growing number of complex biomarkers contributes to costly and delayed decision …

[HTML][HTML] A systematic pan-cancer study on deep learning-based prediction of multi-omic biomarkers from routine pathology images

S Arslan, J Schmidt, C Bass, D Mehrotra… - Communications …, 2024 - nature.com
Background The objective of this comprehensive pan-cancer study is to evaluate the
potential of deep learning (DL) for molecular profiling of multi-omic biomarkers directly from …

Artificial intelligence in clinical oncology: from data to digital pathology and treatment

K Senthil Kumar, V Miskovic, A Blasiak… - American Society of …, 2023 - ascopubs.org
Recently, a wide spectrum of artificial intelligence (AI)–based applications in the broader
categories of digital pathology, biomarker development, and treatment have been explored …

[HTML][HTML] Quantitative digital histopathology and machine learning to predict pathological complete response to chemotherapy in breast cancer patients using pre …

K Saednia, A Lagree, MA Alera, L Fleshner, A Shiner… - Scientific Reports, 2022 - nature.com
Complete pathological response (pCR) to neoadjuvant chemotherapy (NAC) is a prognostic
factor for breast cancer (BC) patients and is correlated with improved survival. However …

[HTML][HTML] Digital pathology and artificial intelligence in translational medicine and clinical practice

V Baxi, R Edwards, M Montalto, S Saha - Modern Pathology, 2022 - Elsevier
Traditional pathology approaches have played an integral role in the delivery of diagnosis,
semi-quantitative or qualitative assessment of protein expression, and classification of …

Artificial intelligence in cancer pathology: Challenge to meet increasing demands of precision medicine

B Lai, J Fu, Q Zhang, N Deng… - … Journal of Oncology, 2023 - spandidos-publications.com
Clinical efforts on precision medicine are driving the need for accurate diagnostic, new
prognostic and novel drug predictive assays to inform patient selection and stratification for …

[HTML][HTML] Deep learning-based prediction of molecular tumor biomarkers from H&E: a practical review

HD Couture - Journal of Personalized Medicine, 2022 - mdpi.com
Molecular and genomic properties are critical in selecting cancer treatments to target
individual tumors, particularly for immunotherapy. However, the methods to assess such …