Phenobarbital for Alcohol Withdrawal Management in the Emergency Department: A Systematic Review of Direct Evidence for the SAEM GRACE Initiative.

K Punia, W Scott, K Manuja, K Campbell… - … : Official Journal of the …, 2023 - europepmc.org
Objectives Alcohol withdrawal syndrome (AWS) is a commonly presenting condition in the
emergency department (ED) and can have severe complications, including mortality …

SAEM GRACE: Phenobarbital for alcohol withdrawal management in the emergency department: A systematic review of direct evidence

K Punia, W Scott, K Manuja, K Campbell… - Academic …, 2024 - Wiley Online Library
Objectives Alcohol withdrawal syndrome (AWS) is a commonly presenting condition in the
emergency department (ED) and can have severe complications, including mortality …

Phenobarbital treatment of alcohol withdrawal in the emergency department: A systematic review and meta‐analysis

CM Lee, DG Dillon, PM Tahir… - Academic Emergency …, 2024 - Wiley Online Library
Objective Despite frequent treatment of alcohol withdrawal syndrome (AWS) in the
emergency department (ED), evidence for phenobarbital (PB) as an ED alternative therapy …

A retrospective evaluation of phenobarbital versus benzodiazepines for treatment of alcohol withdrawal in a regional Canadian emergency department

A Pistore, S Penney, R Bryce, C Meyer, B Bouchard - Alcohol, 2022 - Elsevier
Evidence suggests that phenobarbital can be used to treat alcohol withdrawal syndrome as
monotherapy; however, the therapeutic cornerstone remains benzodiazepines. To date …

Is Phenobarbital an Effective Treatment for Alcohol Withdrawal Syndrome?

B Long, SM Keim, M Gottlieb, N Rathlev - The Journal of Emergency …, 2024 - Elsevier
Background Alcohol use disorder is associated with a variety of complications, including
alcohol withdrawal syndrome (AWS), which may occur in those who decrease or stop …

A Retrospective Evaluation of Adjunctive Phenobarbital vs. Benzodiazepine Alone for the Treatment of Moderate Alcohol Withdrawal in the Emergency Department

JA Lebin, ME Bass, K Heard, J Hoppe… - The Journal of Emergency …, 2024 - Elsevier
Background Phenobarbital has been used in the emergency department (ED) as both a
primary and adjunctive medication for alcohol withdrawal, but previous studies evaluating its …

Management of alcohol withdrawal: time to “SHAKE” things up?

B Borgundvaag, M Klaiman - Canadian Journal of Emergency …, 2020 - cambridge.org
More than three-quarters of Canadians over the age of 15 have consumed beverage alcohol
within the last year. 1 Poured at family gatherings and among friends, gifted for special …

Comparison of phenobarbital-adjunct versus benzodiazepine-only approach for alcohol withdrawal syndrome in the ED

SM Sullivan, BN Dewey, DH Jarrell, N Vadiei… - The American Journal of …, 2019 - Elsevier
Objectives To compare a phenobarbital-adjunct versus benzodiazepine-only approach for
the management of alcohol withdrawal syndrome in the emergency department (ED) with …

Benzodiazepines vs barbiturates for alcohol withdrawal: analysis of 3 different treatment protocols

AC Nelson, J Kehoe, J Sankoff, D Mintzer… - The American journal of …, 2019 - Elsevier
Introduction Alcohol withdrawal treatment varies widely. Benzodiazepines are the standard
of care, with rapid onset and long durations of action. Recent drug shortages involving IV …

Phenobarbital and/or benzodiazepines for recurrent alcohol withdrawal: A self-controlled, retrospective cohort study

A Staidle, C Geier - The American journal of emergency medicine, 2022 - Elsevier
Background While there is ample data supporting the use of barbiturates and
benzodiazepines (BZDs) for the treatment of alcohol withdrawal, there is a paucity of …