Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy
Y Liu, Y Li, Y Wang, C Lin, D Zhang, J Chen… - Journal of Hematology & …, 2022 - Springer
Vascular endothelial growth factor receptors (VEGFRs) are a family of receptor protein
tyrosine kinases that play an important role in the regulation of tumor-induced angiogenesis …
tyrosine kinases that play an important role in the regulation of tumor-induced angiogenesis …
Recent development of multi-target VEGFR-2 inhibitors for the cancer therapy
XJ Liu, HC Zhao, SJ Hou, HJ Zhang, L Cheng… - Bioorganic …, 2023 - Elsevier
Vascular epidermal growth factor receptor-2 (VEGFR-2), as an important tyrosine
transmembrane protein, plays an important role in regulating endothelial cell proliferation …
transmembrane protein, plays an important role in regulating endothelial cell proliferation …
VEGF signaling in cancer treatment
Induction of angiogenesis represents one of the major hallmarks of cancer. The growth of
new vessels is crucial to provide malignant cells with an adequate supply of oxygen and …
new vessels is crucial to provide malignant cells with an adequate supply of oxygen and …
Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non …
PM Lacal, G Graziani - Pharmacological research, 2018 - Elsevier
The vascular endothelial growth factor receptor-1 (VEGFR-1) is a tyrosine kinase receptor
for VEGF-A, VEGF-B, and placental growth factor (PlGF) ligands that is expressed in …
for VEGF-A, VEGF-B, and placental growth factor (PlGF) ligands that is expressed in …
VEGFR-2 inhibitors and the therapeutic applications thereof: a patent review (2012-2016)
FW Peng, DK Liu, QW Zhang, YG Xu… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Angiogenesis is an important component of certain normal physiological
processes, but aberrant angiogenesis contributes to some pathological disorders and in …
processes, but aberrant angiogenesis contributes to some pathological disorders and in …
[HTML][HTML] Interaction between the epidermal growth factor receptor (EGFR) and the vascular endothelial growth factor (VEGF) pathways: a rational approach for multi …
F Ciardiello, T Troiani, R Bianco, M Orditura… - Annals of …, 2006 - Elsevier
Over the last decade, the concept of targeted biological therapy for the treatment of cancer
has emerged. However, a better understanding of these targets and their role in tumor cells …
has emerged. However, a better understanding of these targets and their role in tumor cells …
[HTML][HTML] Clinical advances in the development of novel VEGFR2 inhibitors
C Fontanella, E Ongaro, S Bolzonello… - Annals of …, 2014 - ncbi.nlm.nih.gov
Angiogenesis inhibitors have produced significant advances in the treatment of several
tumors including colorectal, lung, ovarian and renal carcinomas. These agents, however …
tumors including colorectal, lung, ovarian and renal carcinomas. These agents, however …
VEGF-targeted cancer therapy strategies: current progress, hurdles and future prospects
Despite setbacks, the clinical development of antiangiogenic agents has accelerated
remarkably over the past 3–4 years. Consequently, there are currently three direct inhibitors …
remarkably over the past 3–4 years. Consequently, there are currently three direct inhibitors …
Combined inhibition of the VEGFR and EGFR signaling pathways in the treatment of NSCLC
NA Pennell, TJ Lynch Jr - The oncologist, 2009 - academic.oup.com
Multitargeted agents represent the next generation of targeted therapies in solid tumors. The
benefits of individually targeting the vascular endothelial growth factor receptor (VEGFR) …
benefits of individually targeting the vascular endothelial growth factor receptor (VEGFR) …
Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs
Vascular endothelial growth factor receptor (VEGFR) is a very important receptor tyrosine
kinase (RTK) that can induce angiogenesis, increase cell growth and metastasis, reduce …
kinase (RTK) that can induce angiogenesis, increase cell growth and metastasis, reduce …
相关搜索
- vascular endothelial growth factor
- growth factor receptor inhibitors
- epidermal growth factor receptor
- growth factor targeting capabilities
- growth factor therapeutic implication
- growth factor tumor microenvironment
- growth factor cancer cells
- dual vegfr molecule inhibitors
- growth factor vegfr 1
- therapeutic potential and recent advances
- vegf targeted therapy
- tumor therapy receptor inhibitors
- tumor therapy targeting capabilities
- receptor inhibitors targeting capabilities
- tumor microenvironment therapeutic implication
- vegfr 1 therapeutic implication