The inhibition of angiogenesis through vascular endothelial growth factor (VEGF) receptor
targeting is a strategy that is relatively tumour selective. The high selectivity achieved with …

The vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR)
pathways represent 2 clinically validated targets for non–small-cell lung cancer (NSCLC) …

Tumor angiogenesis is a key event that governs tumor progression and metastasis. It is
controlled by the complicated and coordinated actions of pro-angiogenic factors and their …

Vascular endothelial growth factor (VEGF) signaling is critical for tumor angiogenesis.
However, therapies based on inhibition of VEGF receptors (VEGFRs) have shown modest …

Angiogenesis, the formation of blood vessels, is essential for preparing a closed circulatory
system in the body, and for supplying oxygen and nutrition to tissues. Major diseases such …

Vascularization is fundamental to the growth and spread of tumor cells to distant sites. As a
consequence, angiogenesis, the sprouting of new blood vessels from existing ones, is a …

Vascular endothelial growth factor C (VEGF-C) has been identified as a multifaceted factor
participating in the regulation of tumor angiogenesis and lymphangiogenesis. VEGF-C is not …