The development of new drugs to treat painful and inflammatory clinical conditions
continues to be of great interest. The present study evaluated the antinociceptive and anti …

A new quinoline containing selenium, 4‐phenylselenyl‐7‐chloroquinoline (4‐PSQ), was
described and synthetized by our research group. Recently, we demonstrated the potential …

The present study was designed to examine the antinociceptive and anti-inflammatory
effects of 7-chloro-4-phenylsulfonyl quinoline (PSOQ). Mice were orally (po) pretreated with …

The present study evaluated the antinociceptive and anti-inflammatory effects of per oral
(po) administration of salicylic acid-derivative organoselenium compounds in chemical …

Several pathologies, such as pain and inflammation, are modulated by different pathways,
making it necessary to develop drugs capable of modulating different pathways. Based on …

Objective and design: Ebselen, an organoselenium compound is able to modulate the
inflammatory response in rodents. In the present study, the anti-inflammatory and …

The present study examined the acute toxicity and antinociceptive effects of diphenyl
diselenide (PhSe) 2, given orally (po), in chemical and thermical models of pain in mice …

There have been many reports indicating the analgesic and anti‐inflammatory effects of 3, 4‐
dihydroxychalcones. We have designed and synthesized a rigid 3, 4‐dihydroxychalcone …

Monosodium glutamate (MSG) is a neuroexcitatory amino acid commonly used as flavoring
of foods. MSG neonatal administration to animals leads to behavioral and physiological …

The present study was conducted to evaluate the analgesic, antioxidant and anti-
inflammatory effects of two chalcones, 21-hydroxy-2, 41-dimethoxychalcone [2-DMC] and 4 …