Cryptococcus neoformans is an opportunistic fungal pathogen that causes
meningoencephalitis. Previous studies have demonstrated that Cryptococcus binding and …

Cryptococcosis is one of the most important fungal infections of humans. It primarily, but not
exclusively, afflicts people with compromised immune function. Cryptococcosis is most …

Human fungal pathogens cause over 2 million infections per year and are major drivers of
morbidity and mortality. Cryptococcus neoformans and Candida albicans are two of the most …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
infections of the central nervous system. Existing therapies include amphotericin B …

Introduction: Cryptococcosis is one of the most devastating human fungal infections. Despite
its impact, none of the standard antifungals were developed after 1990. New, improved, less …

New drugs are critically needed to treat Cryptosporidium infections, particularly for
malnourished children under 2 years old in the developing world and persons with …

Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis;
however, treatment options remain limited. Here we report the construction of 264 signature …

Cryptococcal meningitis is a significant cause of morbidity and mortality in
immunocompromised patients. VT-1129 is a novel fungus-specific Cyp51 inhibitor with …

Cryptococcal meningoencephalitis (CM) is emerging as an infection in HIV/AIDS patients
shifted from primarily ARTnaive to ART-experienced individuals, as well as patients with …

Cryptococcus neoformans is a fungal pathogen that causes disease in
immunocompromised individuals, especially in HIVC/AIDS patients, and organ transplant …