Objectives We have studied the damage-associated molecular pattern protein S100A4 as a
driver of fibroblast activation in systemic sclerosis (SSc). Methods S100A4 protein …

Occasionally, CA19-9 levels are elevated in serum or bronchoalveolar lavage fluid (BALF) of
patients with idiopathic pulmonary fibrosis (IPF). We have previously seen a case of …

Background There is an increasing number of studies on the diagnostic and prognostic
biomarkers associated with IPF. The purpose of this study was to explore the diagnostic and …

Objective SSc is a rare severe connective tissue disorder. Its prognosis is mainly related to
the development of pulmonary fibrosis (PF)-SSc and pulmonary arterial hypertension. No …

Study objectives To measure surfactant protein-A (SP-A) in the BAL of patients with
idiopathic pulmonary fibrosis (IPF). Design We examined SP-A in BAL and lung tissue of …

Background The aetiology of idiopathic pulmonary fibrosis (IPF) remains poorly understood.
Recent animal studies and epidemiological data have suggested that activation of the …

Abstract Introduction or Hypothesis: The myeloid-associated calgranulins, S100A8, S100A9
and S100A12 are associated with inflammatory lung diseases and S100A9 is proposed as a …

Inflammation is the predominant characteristic of pneumonia. The present study aimed to to
identify a faster and more reliable novel inflammatory marker for the diagnosis of …

Abstract Background/Aims Preclinical studies suggest that the S100A4, a Damage
Associated Molecular Pattern (DAMP) protein upregulated upon stress or injury, may be a …

Objective: Microarray data analysis of PBMCs derived from a cohort of patients with IPF (n=
75) and controls (n= 19) revealed Methods and Results: that S100A12 was upregulated in …