[HTML][HTML] Cell interplay in osteoarthritis

Z Li, Z Huang, L Bai - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Osteoarthritis (OA) is a common chronic disease and a significant health concern that needs
to be urgently solved. OA affects the cartilage and entire joint tissues, including the …

[HTML][HTML] Exosomes in osteoarthritis: Updated insights on pathogenesis, diagnosis, and treatment

WJ Fan, D Liu, LY Pan, WY Wang, YL Ding… - Frontiers in Cell and …, 2022 - frontiersin.org
Osteoarthritis (OA) has maintained a prevalent public health problem worldwide over the
past decades. It is a global challenge because the specific pathogenesis of OA is unclear …

[HTML][HTML] Exosomes rewire the cartilage microenvironment in osteoarthritis: from intercellular communication to therapeutic strategies

Y Wu, J Li, Y Zeng, W Pu, X Mu, K Sun… - International Journal of …, 2022 - nature.com
Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by cartilage loss
and accounts for a major source of pain and disability worldwide. However, effective …

[HTML][HTML] Exosomes: roles and therapeutic potential in osteoarthritis

Z Ni, S Zhou, S Li, L Kuang, H Chen, X Luo, J Ouyang… - Bone research, 2020 - nature.com
Exosomes participate in many physiological and pathological processes by regulating cell–
cell communication, which are involved in numerous diseases, including osteoarthritis (OA) …

Exosome-mediated drug delivery for cell-free therapy of osteoarthritis

L Duan, X Xu, L Xu, H Chen, X Li… - Current medicinal …, 2021 - ingentaconnect.com
Osteoarthritis (OA) is a degenerative disease of cartilage and bones, which results in
severely compromised quality of life in the aged population. However, currently, no ideal …

The dual character of exosomes in osteoarthritis: antagonists and therapeutic agents

Q Zhou, Y Cai, X Lin - Acta Biomaterialia, 2020 - Elsevier
Exosomes have gained increasing attention as they participate in cell cross-talk in
pathological environments and are functional paracrine factors of therapeutic stem cells …

[HTML][HTML] Extracellular vesicles: Potential role in osteoarthritis regenerative medicine

X Wu, Y Wang, Y Xiao, R Crawford, X Mao… - Journal of Orthopaedic …, 2020 - Elsevier
Osteoarthritis (OA) is a prevalent whole joint disease characterised by cartilage degradation,
subchondral bone sclerosis and bone remodelling, and synovium inflammation, leading to …

[HTML][HTML] Exosomes in the pathogenesis, progression, and treatment of osteoarthritis

Y Fan, Z Li, Y He - Bioengineering, 2022 - mdpi.com
Osteoarthritis (OA) is a prevalent and debilitating age-related joint disease characterized by
articular cartilage degeneration, synovial membrane inflammation, osteophyte formation, as …

[HTML][HTML] Extracellular vesicles from mesenchymal stem cells as potential treatments for osteoarthritis

NA Mohd Noor, A Abdullah Nurul… - Cells, 2021 - mdpi.com
Osteoarthritis (OA) is a chronic degenerative disorder of the joint and its prevalence and
severity is increasing owing to ageing of the population. Osteoarthritis is characterized by …

Cartilage repair by mesenchymal stem cell-derived exosomes: preclinical and clinical trial update and perspectives

L Taghiyar, S Jahangir, M Khozaei Ravari… - Cell Biology and …, 2021 - Springer
Osteoarthritis (OA) and other degenerative joint diseases are characterized by articular
cartilage destruction, synovial inflammation, sclerosis of subchondral bone, and loss of …