Mesenchymal stem cell-derived exosomes (MSC-Exos) have been utilized as medicinal
agents or as delivery vehicles in cartilage injuries and cartilage-based diseases. Given the …

Altered subchondral bone and articular cartilage interactions have been implicated in the
pathogenesis of osteoarthritis (OA); however, the mechanisms remain unknown. Exosomes …

Structural disturbances of the subchondral bone are a hallmark of osteoarthritis (OA),
including sclerotic changes, cystic lesions, and osteophyte formation. Osteocytes act as …

Osteoarthritis (OA) is an inflammatory condition still lacking effective treatments.
Mesenchymal stem/stromal cells (MSCs) have been successfully employed in pre-clinical …

This year in review on osteoarthritis biology summarizes a series of research articles
published between the 2020 and 2021 Osteoarthritis Research Society International …

Osteoarthritis (OA) is a disease of an entire synovial joint characterized by clinical symptoms
and distortion of joint tissues, including cartilage, muscles, ligaments, and bone. Although …

This year in review about osteoarthritis biology highlights a selection of articles published
between the 2019 and 2020 Osteoarthritis Research Society International (OARSI) World …

Extracellular vesicles have emerged as vehicles for the exchange of bioactive signaling
molecules within cartilage and between joint tissues to promote joint homeostasis and …

Mesenchymal stem or stromal cells (MSCs) exert chondroprotective effects in preclinical
models of osteoarthritis (OA). Most of their therapeutic effects are mediated via soluble …

Mesenchymal stem cell (MSC) therapies have demonstrated efficacy in cartilage repair in
animal and clinical studies. The efficacy of MSC-based therapies which was previously …