Osteoarthritis (OA), the most ubiquitous degenerative disease affecting the entire joint, is
characterized by cartilage degradation and synovial inflammation. Although the …

With the insufficient satisfaction rates and high cost of operative treatment for osteoarthritis
(OA), alternatives have been sought. Furthermore, the inability of current medications to …

Within the field of regenerative medicine, many have sought to use stem cells as a promising
way to heal human tissue; however, in the past few years, exosomes (packaged vesicles …

Understanding the molecular drivers and feedback loops of osteoarthritis (OA) may provide
future therapeutic strategies to modulate the disease progression. The current paradigm of …

Rheumatoid arthritis is a well-known chronic inflammatory joint disorder. It encompasses
systemic inflammation, autoimmunity and development of several joint abnormalities leading …

Targeted delivery to the diseased cell or tissue is the key to the successful clinical use of
nucleic acid drugs. In particular, delivery of microRNA-140 (miRNA-140, miR-140) into …

Osteoarthritis (OA) has become recognized as a low-grade inflammatory state. Inflammatory
infiltration of the synovium by macrophages, T cells, B cells, and other immune cells is often …

Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder that causes systemic
inflammation, autoimmunity, and joint abnormalities that result in permanent disability …

Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Osteoarthritis (OA) is a degenerative joint disease in the elderly. Although OA has been
considered as primarily a disease of the articular cartilage, the participation of subchondral …