Measuring anxiety-like behaviors in rodent models of traumatic brain injury

LB Tucker, JT McCabe - Frontiers in behavioral neuroscience, 2021 - frontiersin.org
Anxiety is a common complaint following acquired traumatic brain injury (TBI). However, the
measurement of dysfunctional anxiety behavioral states following experimental TBI in …

Long-term effects of traumatic brain injury on anxiety-like behaviors in mice: behavioral and neural correlates

J Popovitz, SP Mysore, H Adwanikar - Frontiers in behavioral …, 2019 - frontiersin.org
Traumatic brain injury (TBI) has been frequently linked to affective disorders such as anxiety
and depression. However, much remains to be understood about the underlying molecular …

Traumatic brain injury–modeling neuropsychiatric symptoms in rodents

O Malkesman, LB Tucker, J Ozl, JT McCabe - Frontiers in neurology, 2013 - frontiersin.org
Each year in the US,∼ 1.5 million people sustain a traumatic brain injury (TBI). Victims of TBI
can suffer from chronic post-TBI symptoms, such as sensory and motor deficits, cognitive …

Neuropsychiatric symptom modeling in male and female C57BL/6J mice after experimental traumatic brain injury

LB Tucker, JF Burke, AH Fu, JT McCabe - Journal of neurotrauma, 2017 - liebertpub.com
Psychiatric symptoms such as anxiety and depression are frequent and persistent
complaints following traumatic brain injury (TBI). Modeling these symptoms in animal …

Experimental traumatic brain injury induces a pervasive hyperanxious phenotype in rats

NC Jones, L Cardamone, JP Williams… - Journal of …, 2008 - liebertpub.com
Mood disturbances, including depression and anxiety disorders, are common and disabling
long-term sequelae of traumatic brain injury (TBI). These psychiatric conditions have …

Clinical relevance of behavior testing in animal models of traumatic brain injury

SR Shultz, SJ McDonald, F Corrigan… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of morbidity worldwide, with patients often
suffering from consequences such as cognitive deficits, social abnormalities, anxiety …

[HTML][HTML] A role for the amygdala in impairments of affective behaviors following mild traumatic brain injury

TA McCorkle, JR Barson, R Raghupathi - Frontiers in behavioral …, 2021 - frontiersin.org
Mild traumatic brain injury (TBI) results in chronic affective disorders such as depression,
anxiety, and fear that persist up to years following injury and significantly impair the quality of …

Traumatic brain injury-induced submissive behavior in rats: link to depression and anxiety

M Boyko, BF Gruenbaum, I Shelef… - Translational …, 2022 - nature.com
Traumatic brain injury (TBI) affects millions of people worldwide, many of whom are affected
with post-TBI mood disorders or behavioral changes, including aggression or social …

Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies

JL McGuire, LB Ngwenya, RE McCullumsmith - Molecular Psychiatry, 2019 - nature.com
Traumatic brain injury (TBI) is a pervasive problem in the United States and worldwide, as
the number of diagnosed individuals is increasing yearly and there are no efficacious …

[HTML][HTML] A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice

SA Torrisi, G Lavanco, OM Maurel, W Gulisano… - Neurobiology of …, 2021 - Elsevier
Translational animal models for studying post-traumatic stress disorder (PTSD) are valuable
for elucidating the poorly understood neurobiology of this neuropsychiatric disorder. These …