In vivo functional genomics of Pseudomonas aeruginosa for high‐throughput screening of new virulence factors and antibacterial targets

E Potvin, DE Lehoux, I Kukavica‐Ibrulj… - Environmental …, 2003 - Wiley Online Library
Pseudomonas aeruginosa is a model for studying opportunistic pathogens that are highly
resistant to most classes of antibiotics and cause chronic pulmonary infections. We have …

[HTML][HTML] Comparison of type III secretion system virulence among fluoroquinolone-susceptible and-resistant clinical isolates of Pseudomonas aeruginosa

A Wong-Beringer, J Wiener-Kronish, S Lynch… - Clinical microbiology …, 2008 - Elsevier
Fluoroquinolone resistance and type III secretion system (TTSS) virulence are
independently associated in Pseudomonas aeruginosa infections with poor patient …

Escherichia coli Sequence Type 410 Is Causing New International High-Risk Clones

L Roer, S Overballe-Petersen, F Hansen, K Schønning… - Msphere, 2018 - Am Soc Microbiol
Escherichia coli sequence type 410 (ST410) has been reported worldwide as an
extraintestinal pathogen associated with resistance to fluoroquinolones, third-generation …

Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa

MC Wolfgang, BR Kulasekara… - Proceedings of the …, 2003 - National Acad Sciences
Pseudomonas aeruginosa is a ubiquitous environmental bacterium capable of causing a
variety of life-threatening human infections. The genetic basis for preferential infection of …

[HTML][HTML] A type III secretion negative clinical strain of Pseudomonas aeruginosa employs a two-partner secreted exolysin to induce hemorrhagic pneumonia

S Elsen, P Huber, S Bouillot, Y Couté, P Fournier… - Cell host & …, 2014 - cell.com
Virulence of Pseudomonas aeruginosa is typically attributed to its type III secretion system
(T3SS). A taxonomic outlier, the P. aeruginosa PA7 strain, lacks a T3SS locus, and no …

The Population Structure of Pseudomonas aeruginosa Is Characterized by Genetic Isolation of exoU+ and exoS+ Lineages

EA Ozer, E Nnah, X Didelot, RJ Whitaker… - Genome biology and …, 2019 - academic.oup.com
The diversification of microbial populations may be driven by many factors including
adaptation to distinct ecological niches and barriers to recombination. We examined the …

[HTML][HTML] Pseudomonas aeruginosa reference strains PAO1 and PA14: A genomic, phenotypic, and therapeutic review

A Grace, R Sahu, DR Owen, VA Dennis - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa is a ubiquitous, motile, gram-negative bacterium that has been
recently identified as a multi-drug resistant pathogen in critical need of novel therapeutics. Of …

[HTML][HTML] Molecular analysis of Pseudomonas aeruginosa isolated from clinical, environmental and cockroach sources by ERIC-PCR

O Zarei, L Shokoohizadeh, H Hossainpour… - BMC research …, 2018 - Springer
Objective The objective of this study was to investigate the antibiotic susceptibility, virulence
factors and clonal relationship among Pseudomonas aeruginosa isolated from …

[HTML][HTML] Comparative genomics of clinical strains of Pseudomonas aeruginosa strains isolated from different geographic sites

D Subedi, AK Vijay, GS Kohli, SA Rice, M Willcox - Scientific reports, 2018 - nature.com
The large and complex genome of Pseudomonas aeruginosa, which consists of significant
portions (up to 20%) of transferable genetic elements contributes to the rapid development …

Clinical outcomes of type III Pseudomonas aeruginosa bacteremia

AA El-Solh, A Hattemer, AR Hauser… - Critical care …, 2012 - journals.lww.com
Background: Pseudomonas aeruginosa bacteremia is a serious and life-threatening
infection associated with high mortality. Among the multitude of virulence determinants …