The complex regulation of eNOS (endothelial nitric oxide synthase) in cardiovascular
physiology occurs at multiple stages. eNOS mRNA levels are controlled both at the …

Rationale: Endothelial dysfunction is an early event in cardiovascular disease and
characterized by reduced production of nitric oxide (NO). The F-BAR protein NO synthase …

The endothelial isoform of nitric oxide synthase (eNOS) has been well recognized for its
central role in conserving vascular homeostasis by inducing quiescence of endothelial cells …

ABSTRACT NO, produced by the endothelium, is a modulator of vascular inflammation.
Traditionally, eNOS was believed to be the primary source of NO in the endothelium …

There is substantial evidence supporting the idea that the process of angiogenesis requires
the synthesis of endothelium-derived nitric oxide (NO). NO, characterized as a major …

NO produced by endothelial NO synthase (eNOS) plays important roles in the regulation of
vascular tone and structure. The purpose of this study was to clarify the role of eNOS-derived …

Endothelial nitric oxide synthase (eNOS), the major nitric oxide (NO)-generating enzyme of
the vasculature, is regulated through multiple interactions with proteins, including caveolin …

The pathogenesis of many cardiovascular diseases is associated with reduced nitric oxide
(NO) bioavailability and/or increased endothelial NO synthase (eNOS)-dependent …

High levels of NO generated in the vasculature under inflammatory conditions are usually
attributed to inducible nitric-oxide synthase (iNOS), but the role of the constitutively …

Background: Oxidative stress is critical for the fibrotic response of mesangial cells (MCs) to
angiotensin II. Results: Nox4-and mitochondrial reactive oxygen species (ROS)-dependent …