Introduction Hereditary spastic paraplegias (HSP) include a clinically and genetically
heterogeneous group of conditions. Novel imaging modalities have been increasingly …

Hereditary spastic paraplegias (HSP) are a large group of genetic diseases characterized by
progressive degeneration of the long tracts of the spinal cord, namely the corticospinal tracts …

Hereditary spastic paraplegias (HSP) are a group of genetically and clinically
heterogeneous neurologic disorders. Hereby we describe a relatively large group of patients …

Hereditary spastic paraplegia (HSP) is characterized by progressive lower limb spasticity.
There is no disease-modifying treatment currently available. Therefore, standardized …

Purpose To investigate whether specific patterns of brain gray matter (GM) regional volumes
and white matter (WM) microstructural abnormalities and spinal cord atrophy occur in …

ABSTRACT Introduction: Hereditary spastic paraplegias (HSPs) are heterogeneous
neurodegenerative disorders characterized by progressive lower limb weakness and …

Hereditary spastic paraplegias (HSPs) are a clinically and genetically heterogeneous group
of neurodegenerative disorders characterized by progressive spasticity and weakness of the …

Background Hereditary spastic paraplegias (HSP) are a composite and genetically
heterogeneous group of conditions mainly expressed by the impairment of the central motor …

Hereditary spastic paraplegias (HSPs) are clinically and genetically heterogeneous
neurodegenerative disorders. Numerous genes linked to HSPs, overlapping phenotypes …

Purpose Hereditary spastic paraplegia (HSP) and hereditary spastic ataxia (HSA) are a
heterogeneous group of genetic disorders characterized by progressive lower limb spasticity …