Dietary obesity in nine inbred mouse strains

DB West, CN Boozer, DL Moody… - American Journal of …, 1992 - journals.physiology.org
The effect of 7 wk consumption of a diet containing 32.6% of kilocalories as fat [condensed
milk (CM) diet] on body composition and energy intake was evaluated in nine strains of …

Response of C57Bl/6 mice to a carbohydrate-free diet

S Borghjid, RD Feinman - Nutrition & metabolism, 2012 - Springer
High fat feeding in rodents generally leads to obesity and insulin resistance whereas in
humans this is only seen if dietary carbohydrate is also high, the result of the anabolic effect …

The development of obesity in genetically diabetic-obese (db/db) mice pair-fed with lean siblings: The importance of thermoregulatory thermogenesis

P Trayhurn, L Fuller - Diabetologia, 1980 - Springer
The importance of reduced thermoregulatory thermogenesis as a mechanism for the high
metabolic efficiency of the diabetic-obese (db/db) mouse has been investigated. Young …

Food intake and energy expenditure are increased in high-fat-sensitive but not in high-carbohydrate-sensitive obesity-prone rats

D Azzout-Marniche, C Chaumontet… - American Journal …, 2014 - journals.physiology.org
Obesity-prone (OP) rodents are used as models of human obesity predisposition. The goal
of the present study was to identify preexisting defects in energy expenditure components in …

A difference in fatty acid composition of isocaloric high-fat diets alters metabolic flexibility in male C57BL/6JOlaHsd mice

LPM Duivenvoorde, EM van Schothorst, HM Swarts… - PLoS …, 2015 - journals.plos.org
Poly-unsaturated fatty acids (PUFAs) are considered to be healthier than saturated fatty
acids (SFAs), but others postulate that especially the ratio of omega-6 to omega-3 PUFAs …

The development of obesity, hyperinsulinemia, and hyperglycemia in ob/ob mice

PU Dubuc - Metabolism, 1976 - Elsevier
The development of obesity, hyperglycemia, and hyperinsulinemia was examined in obese-
hyperglycemic (ob/ob) mice, their lean littermates, and homozygous lean mice (+/+) between …

Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice

K Almind, CR Kahn - Diabetes, 2004 - Am Diabetes Assoc
Diet-induced obesity is the primary determinant of the current epidemic of diabetes. We have
explored the role of genetics in this phenomenon, using C57Bl/6 (B6), 129S6/SvEvTac …

Initiation and perpetuation of obesity and obesity resistance in rats

BE Levin, S Hogan, AC Sullivan - American Journal of …, 1989 - journals.physiology.org
A search was made for predisposing factors and sequelae of diet-induced obesity (DIO) or
resistance to DIO (DR). During 3 mo on a high-energy (CM) diet, two-thirds of the male …

Characterization of β‐Cell Mass and Insulin Resistance in Diet‐induced Obese and Diet‐resistant Rats

SJ Paulsen, J Jelsing, AN Madsen, G Hansen… - …, 2010 - Wiley Online Library
The selectively bred diet‐induced obese (DIO) and diet‐resistant (DR) rats represent a
polygenetic animal model mimicking most clinical variables characterizing the human …

Age-related changes in lipid and carbohydrate metabolism of the genetically obese mouse

LA Menahan - Metabolism, 1983 - Elsevier
Abstract Obese mice (C57BL 6J ob ob) and their lean controls were studied longitudinally
from immediately post-weaning until 62 wk of age, at which time the experiment was …