The objective of this study was to determine the optimal conditions under which to assess
glucose tolerance in chow-and high-fat-fed C57BL/6J mice. Mice were fed either chow or …

ABSTRACT The New Zealand obese (NZO) mouse is an excellent and well established
model of obesity, glucose intolerance, and the metabolic syndrome as it exhibits classical …

We investigated the short-term (7 days) and long-term (60 days) metabolic effect of high fat
diet induced obesity (DIO) and weight gain in isogenic C57BL/6 mice and examined the …

Obesity-resistant (non-responder, NR) phenotypes that exhibit reduced susceptibility to
developing obesity despite being exposed to high dietary fat are crucial in exploring the …

Diabetes and lean control mice of two strains (C57BL/6J and C57BL/KsJ) were tested for
their ability to regulate food intake and body weight when subjected to caloric deficits and …

To investigate mechanisms of resistance to obesity, the physiologic responses to short-term
moderate fat feeding were studied at ambient temperature (Ta)= 23° C and thermonuetrality …

AKR/J and SWR/J inbred mice differ markedly in their sensitivity to dietary obesity. Male
AKR/J mice increase adiposity approximately threefold, whereas SWR/J remain relatively …

The M16 line of mice, selected for rapid postweaning gain, exhibits polygenically controlled
obesity and hyperphagia. The effect of limiting postweaning energy intake on the …

Metabolic flexibility is defined as the ability to adapt substrate oxidation rates in response to
changes in fuel availability. The inability to switch between the oxidation of lipid and …

Life-long sequential changes in glucose tolerance and insulin secretion were investigated in
genetically obese Zucker rats (fa/fa) fed a diabetogenic diet rich in lard and sucrose …