Metabolic Characteristics and Body Composition in a Model of Anti‐Obese Rats (Lou/C)

K Couturier, S Servais, H Koubi, B Sempore… - Obesity …, 2002 - Wiley Online Library
Objective: The aims of this study were to investigate some features of the metabolic profile
and the body composition of male Lou/C rats and to examine whether these characteristics …

Resolution of glucose intolerance in long-term high-fat, high-sucrose-fed mice

G Kowalski, MJ Kraakman, S Mason, AJ Murphy… - 2017 - dro.deakin.edu.au
The high-fat, high-sucrose diet (HFSD)-fed C57Bl/6 mouse is a widely used model of
prediabetes. However, studies typically implement a relatively short dietary intervention …

Not so fast: paradoxically increased variability in the glucose tolerance test due to food withdrawal in continuous glucose-monitored mice

WB Rubio, MD Cortopassi, D Ramachandran… - Molecular …, 2023 - Elsevier
Objective This study was performed to determine the effect of fasting on reproducibility of the
glucose tolerance test. Due to individual variation in animal feeding behaviors, fasting …

Genetic analysis of obesity-induced diabetes associated with a limited capacity to synthesize insulin in C57BL/KS mice: evicence for polygenic control

K Kaku, M Province, MA Permutt - Diabetologia, 1989 - Springer
Expression of obesity-induced diabetes associated with the diabetes or db mutation in mice
varies in inbred strains. This study utilized a genetic analysis to evaluate the number of …

Energy expenditure is reduced in preobese 2-day Zucker fa/fa rats

BJ Moore, SJ Armbruster… - American Journal of …, 1985 - journals.physiology.org
The rate of oxygen consumption was measured in 2-day Zucker preobese (fa/fa),
homozygous (Fa/Fa) lean, and lean rats of unknown genotype (Fa/?) over the ambient …

Changes in gene expression foreshadow diet-induced obesity in genetically identical mice

RA Koza, L Nikonova, J Hogan, JS Rim… - PLoS …, 2006 - journals.plos.org
High phenotypic variation in diet-induced obesity in male C57BL/6J inbred mice suggests a
molecular model to investigate non-genetic mechanisms of obesity. Feeding mice a high-fat …

C57BL/6J and A/J mice fed a high‐fat diet delineate components of metabolic syndrome

C Gallou‐Kabani, A Vigé, MS Gross, JP Rabès… - …, 2007 - Wiley Online Library
Objective: The aim of this study was to assess the suitability of A/J and C57BL/6J mice of
both sexes as models of some components of the human metabolic syndrome (MetS) under …

[HTML][HTML] Lessons from rodent models of obesity

MG Myers, RL Leibel - 2015 - europepmc.org
Rodent models in which monogenic alterations cause obesity in the absence of
environmental changes have confirmed earlier inferences regarding the biologic/genetic …

Variation in type 2 diabetes-related traits in mouse strains susceptible to diet-induced obesity

M Rossmeisl, JS Rim, RA Koza, LP Kozak - Diabetes, 2003 - Am Diabetes Assoc
C57BL/6J (B6) and AKR/J (AKR) inbred strains of mice develop a comparable degree of
obesity when fed a high-fat diet. However, although obese B6 mice are more glucose …

Energy expenditure in obesity-prone and obesity-resistant rats before and after the introduction of a high-fat diet

MR Jackman, PS MacLean… - American Journal of …, 2010 - journals.physiology.org
While most rats gain weight when placed on a high-fat diet (HFD), some strains resist HFD-
induced weight gain. To maintain weight, obesity-resistant (OR) rats must either eat less …